Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

A cross-institutional team of scientists developed PeakQC, a new software tool for automated quality control of mass spectrometry data.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.

A team of researchers from Pacific Northwest National Laboratory and the Environmental Molecular Sciences Laboratory developed a new and flexible software tool called “Advanced Spectra PCA Toolbox.”

Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for both sexes.

Three PNNL-affiliated researchers have been named fellows of the American Association for the Advancement of Science, the world’s largest multidisciplinary scientific society.

Scientists have learned more about how to protect the insulin-producing cells that die in patients with Type 1 diabetes.

PNNL researchers helped identify a fragment from the SARS-CoV-2 virus that spurs severe illness.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

PNNL’s Nick Ward has been honored with the American Geophysical Union’s Thomas Hilker Early Career Award.

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

Scientists have opened a new view into the workings of the central nervous system, finding a diverse set of important molecules.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Small teams in the Biological Sciences Division at PNNL and at EMSL—the Environmental and Molecular Sciences Laboratory, an Office of Science user facility at PNNL—are pros at preparation.

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.