PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Three PNNL technologies have been declared winners of 2025 Federal Laboratory Consortium Awards, named for a program that recognizes federal laboratories and their industry partners for outstanding technology transfer achievements.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

A cross-institutional team of scientists developed PeakQC, a new software tool for automated quality control of mass spectrometry data.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.

A team of researchers from Pacific Northwest National Laboratory and the Environmental Molecular Sciences Laboratory developed a new and flexible software tool called “Advanced Spectra PCA Toolbox.”

Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for both sexes.

Three PNNL-affiliated researchers have been named fellows of the American Association for the Advancement of Science, the world’s largest multidisciplinary scientific society.

Scientists have learned more about how to protect the insulin-producing cells that die in patients with Type 1 diabetes.

PNNL helps deliver efficiency-related rules and requirements that steadily improve performance of America’s buildings, saving energy and costs and reducing carbon emissions.

PNNL researchers helped identify a fragment from the SARS-CoV-2 virus that spurs severe illness.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

PNNL’s Andrea Mengual co-chaired a working group that produced Building Performance Standards: A Technical Resource Guide. PNNL’s Kim Cheslak, Bing Liu, and Jian Zhang contributed to the effort.

Scientists have opened a new view into the workings of the central nervous system, finding a diverse set of important molecules.

The PNNL-managed Building America Solution Center translates research into actionable considerations for homeowners and builders to provide two solutions in one: increasing energy efficiency while also enhancing disaster resistance.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.