Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

Models have identified a new source of anthropogenic emissions driving the observed weakening of the Atlantic Meridional Overturning Circulation.

Less pollution and the odd shapes of snow grains as they pack together should help cut the decline of snowpack later this century.

In a new paper, researchers point to three major efforts where the biggest climate mitigation gains stand to be realized: ramping up carbon dioxide removal, reigning in non-carbon dioxide emissions and halting deforestation.

A new discovery by PNNL researchers has illuminated a previously unknown key mechanism that could inform the development of new, more effective catalysts for abating NOx emissions from combustion-engines burning diesel or low carbon fuel.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

The Co-Optimization of Fuels & Engines initiative recently outlined six years of research in a findings and impact report.

PNNL catalysis expert Yong Wang has assumed an associate editor role for the Chemical Engineering Journal.