Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

PNNL's Alison Colotelo receives award from the National Hydropower Association on behalf of Salmon Summit team at the 2024 Clean Currents conference.

A cross-institutional team of scientists developed PeakQC, a new software tool for automated quality control of mass spectrometry data.

A new mini-acoustic transmitter and tagging procedure is able to provide data on small, sensitive fish species like the American shad.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

Scientists have developed a way to detect tiny amounts of hard-to-detect explosives more than eight feet away.

A team of researchers from Pacific Northwest National Laboratory and the Environmental Molecular Sciences Laboratory developed a new and flexible software tool called “Advanced Spectra PCA Toolbox.”

Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for both sexes.

Three PNNL-affiliated researchers have been named fellows of the American Association for the Advancement of Science, the world’s largest multidisciplinary scientific society.

New methodological approach demonstrates how to assess the economic value, including non-traditional value streams, of converting non-powered dams to hydroelectric facilities.

New research identifies the most important factors in successful fish passage, pointing toward new options for flexible dam operations.

Scientists have learned more about how to protect the insulin-producing cells that die in patients with Type 1 diabetes.

PNNL researchers helped identify a fragment from the SARS-CoV-2 virus that spurs severe illness.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

Developed with community input, the new Hydropower Vision Roadmap lays out a path to achieve a shared vison for modern hydropower by 2050.

Scientists have opened a new view into the workings of the central nervous system, finding a diverse set of important molecules.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Small teams in the Biological Sciences Division at PNNL and at EMSL—the Environmental and Molecular Sciences Laboratory, an Office of Science user facility at PNNL—are pros at preparation.