Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

Scientists at PNNL have published a new article that focuses on understanding the composition, dynamics, and deployment of beneficial soil microbiomes to get the most out of soil.

A team of researchers from PNNL provided technical knowledge and support to test a suite of techniques that detect genetically modified bacteria, viruses, and cells.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

SAGE is a high-efficiency genome integration strategy for bacteria that makes the stable introduction of new traits simple for newly discovered microbes.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.