Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

By combining computational modeling with experimental research, scientists identified a promising composition that reduces the need for a critical material in an alloy that can withstand extreme environments.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

The Pacific Northwest Association of Toxicologists (PANWAT) presented its annual Toxicology Achievement Award to Katrina Waters at the Society of Toxicology Pacific Northwest Chapter Meeting, held in Lynnwood, Washington, on September 30th.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

Kriston Brooks received the 2023 Department of Energy Office of Classification Outstanding DC Award, which is given to those in the classification community who have made significant contributions.

Senior Advisor Isabella van Rooyen shares her journey from child to internationally recognized scientist in nuclear materials and manufacturing.

Harish Gadey, David Peeler, and Tom Brouns named to Waste Management Symposia Program Advisory Committee positions to help develop radioactive waste management discussions.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

Bradley Crowell with the U.S. Nuclear Regulatory Commission sees advanced materials integrity, radiological measurement, and environmental capabilities on his first visit to PNNL.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Lauren Charles, a chief data scientist at PNNL, joined the editorial board of the largest open access journal published by Nature Research.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

PNNL’s ARENA test bed analyzes how electrical cables degrade in extreme environments and how nondestructive examination inspection technologies can detect and locate damage.

PNNL researchers explore the feasibility of using low-flying drones to survey sites for low levels of radiation.