Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

The Center for Continuum Computing at PNNL aims to integrate cloud platforms, high-performance computing, and edge devices into a seamless ecosystem that accelerates scientific discovery.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL’s Center for Cloud Computing is addressing challenges in data management and hybrid cloud solutions with industry and academic partnerships.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

A cross-institutional team of scientists developed PeakQC, a new software tool for automated quality control of mass spectrometry data.

PNNL has developed a decision tool that provides contractors and installers with the information they need to properly select and install cold climate heat pumps, which are a key technology for achieving decarbonization.

In soil, microbes produce and consume methane. Using a technique called pool dilution, researchers can separate the rate of methane production and consumption from the net rate.

PNNL helps deliver efficiency-related rules and requirements that steadily improve performance of America’s buildings, saving energy and costs and reducing carbon emissions.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.

Leaders from the DOE Office of Energy Efficiency and Renewable Energy visited PNNL October 19–20 for a firsthand look at capabilities and research progress.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.