Non-Targeted Effects Induced by Ionizing Radiation: Mechanisms and Potential Impact on Radiation Induced Health Effects

January 1, 2015

Journal Article

Non-Targeted Effects Induced by Ionizing Radiation: Mechanisms and Potential Impact on Radiation Induced Health Effects

Abstract

Not-targeted effects represent a paradigm shift from the "DNA centric" view that ionizing radiation only elicits biological effects and subsequent health consequences as a result of an energy deposition event in the cell nucleus. While this is likely true at higher radiation doses (> 1Gy), at low doses (

Revised: January 27, 2015 | Published: January 1, 2015

Citation

Morgan W.F., and M.B. Sowa. 2015. Non-Targeted Effects Induced by Ionizing Radiation: Mechanisms and Potential Impact on Radiation Induced Health Effects. Cancer Letters 356, no. 1:17-21. PNNL-SA-98283. doi:10.1016/j.canlet.2013.09.009