PNNL

Abstract

In this chapter, the reviews on biosensor development based on 1-D nanomaterials, CNTs, semiconducting nanowires, and some cantilevers will be introduced. The emphasis of this review will be placed on CNTs and electrochemical/electronic biosensor developments. Section 2 of this chapter gives a detailed description of carbon nanotubes-based biosensor development, from fabrication of carbon nanotubes, the strategies for construction of carbon nanotube based bisosensros to their bioappplications. In the section of the applications of CNTs based biosensors, various detection principles, e. g. electrochemical, electronic, and optical method, and their applications are reviewed in detail. Section 3 introduces the method for synthesis of semiconducting nanowires, e.g. silicon naowires, conducting polymer nanowires and metal oxide nanowires and their applications in DNA and proteins senseing. Section 4 simply describes the development for nanocantilevers based biosensors and their application in DNA and protein dignosis. Each section starts from a brief introduction and then goes into details. Finally in the Conclusion section, the development of 1-D nanomaterials based biosensor development is summarized.