January 1, 2009
Journal Article

Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures

Abstract

This manuscript highlights research focused on the development of field-deployable analytical instruments based on EC detection. Background information and a general overview of EC detection methods and integrated use of nanomaterials in the development of these sensors are provided. New developments in EC sensors using various types of screen-printed electrodes, integrated nanomaterials, and immunoassays are discussed. Recent applications of EC sensors for assessing exposure to pesticides or detecting biomarkers of disease are highlighted to demonstrate the ability to monitor chemical metabolites, enzyme activity, or protein biomarkers of disease. In addition, future considerations and opportunities for advancing the use of EC platforms for dosimetric studies are covered.

Revised: June 28, 2010 | Published: January 1, 2009

Citation

Barry R.C., Y. Lin, J. Wang, G. Liu, and C. Timchalk. 2009. Nanotechnology-Based Electrochemical Sensors for Biomonitoring Chemical Exposures. Journal of Exposure Science and Environmental Epidemiology 19. PNNL-SA-59427. doi:10.1038/jes.2008.71