While the role of miRNAs in establishing and maintaining the developing nervous system is widely appreciated, the developmental neurobehavioral role of miRNAs has yet to be defined. Here we show that transient disruption of brain morphogenesis by ethanol exposure results in behavioral hyperactivity in larval zebrafish challenged with changes in lighting conditions.
Revised: July 18, 2012 |
Published: April 1, 2012
Citation
Tal T., J. Franzosa, S.C. Tilton, K.A. Philbrick, U.T. Iwaniec, U.T. Iwaniec, and R.T. Turner, et al. 2012.MicroRNAs Control Neurobehavioral Development and Function in Zebrafish.FASEB Journal 26, no. 4:1452-1461. PNWD-SA-9473. doi:10.1096/fj.11-194464