Here we report a new thermosensitive aqueous solution of polycaprolactone-grafted-polyethylene glycol (PCL-g-PEG) polymer which is a sol at low temperature and a gel at human body temperature (37°C). Rheological measurements indicate that gels with tunable mechanical properties (0.05 to 3300 Pa) can be obtained at 37°C by varying polymer concentrations.
Revised: April 4, 2013 |
Published: January 30, 2013
Citation
Lin G., L. Cosimbescu, N.J. Karin, A. Gutowska, and B.J. Tarasevich. 2013.Injectable and thermogelling hydrogels of PCL-g-PEG: mechanisms, rheological and enzymatic degradation properties.Journal of Materials Chemistry B 1, no. 9:1249-1255. PNWD-SA-9299. doi:10.1039/C2TB00468B