May 1, 2018
Journal Article

Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions

Abstract

The Foglio Bonda et al. (2016) (henceforth FB) paper discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (the response variable of interest). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). After publication of the FB paper, the second author of this corrigendum (not an author of the original paper) contacted the corresponding author to point out some errors as well as insufficient explanations in parts of the paper. This corrigendum was prepared to address these issues. The authors of the original paper apologize for any inconveniences to readers.

Revised: May 14, 2019 | Published: May 1, 2018

Citation

Pattarino F., G.F. Piepel, and M. Rinaldi. 2018. Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions. European Journal of Pharmaceutical Sciences 117. PNNL-SA-123916. doi:10.1016/j.ejps.2018.03.005