In recent years, mass spectroscopy imaging (MSI) has emerged as a foundational technique in metabolomics and drug screening providing deeper understanding of complex mechanistic pathways within biochemical systems and biological organisms. We have been invited to contribute a chapter to a new Springer series volume, entitled “Mass Spectrometry Imaging of Small Molecules”. The volume is planned for the highly successful lab protocol series Methods in Molecular Biology, published by Humana Press, USA. The volume is aimed to equip readers with step-by-step mass spectrometric imaging protocols and bring rapidly maturing methods of MS imaging to life science researchers. The chapter will provide a detailed protocol of ambient MSI by use of nanospray desorption electrospray ionization.
Revised: May 12, 2015 |
Published: January 17, 2015
Citation
Lanekoff I., and J. Laskin. 2015.Imaging of Lipids and Metabolites Using Nanospray Desorption Electrospray Ionization Mass Spectrometry. In Mass Spectrometry Imaging of Small Molecules: Methods in Molecular Biology, edited by L He. 99-106. New York:Springer.PNNL-SA-93033.