This project developed a new concept for medical isotopes production that offers an alternative to reactor-based and accelerator-based technologies and is expected to cost-effectively produce “neutron capture” medical isotopes such as, for example, 177Lu, 125I, 99Tc, and 103Pd, which are used for cancer therapy including prostate cancer. The concept provides for using a neutron flux, like reactor technologies, to make the isotopes of interest. However, the neutron flux is generated by a machine, the Alternative Method for Producing Medical Isotopes (AMPMI) technology, not by a reactor making the technology more applicable.