February 1, 2011
Journal Article

Enzyme entrapped nanoporous scaffolds formed through flow induced gelation in microfluidic filter device for sensitive biosensing of organophosphorus compounds

Abstract

A novel and versatile processing method was developed for the formation of gel scaffolds with in-situ AChE-AuNPs immobilization for biosensing of organophosphorus compounds. The biosensor designed by our new approach shows high sensitivity, selectivity and reactivation efficiency. This flow induced immobilziation technique opens up new pathways for designing simple, fast, biocompatible, and cost-effective process for enhanced sensor performance and on-site testing of a variety of toxic organophosphorus compounds.

Revised: February 17, 2011 | Published: February 1, 2011

Citation

Lu D., G. Shao, D. Du, J. Wang, L. Wang, W. Wang, and Y. Lin. 2011. Enzyme entrapped nanoporous scaffolds formed through flow induced gelation in microfluidic filter device for sensitive biosensing of organophosphorus compounds. Lab on a Chip 11, no. 3:381-384. PNNL-SA-76783. doi:10.1039/C0LC00337A