Modern biological research often requires massively parallel experiments to analyze a large number of samples in order to find biomarkers, screen drugs, or elucidate complex cellular pathways. These processes frequently involve time-consuming sample preparation and expensive biochemical measurements. Another constraint frequently encountered in bioanalysis is limited amounts of available sample. Microfluidics or lab-on-a-chip platforms offer promise for addressing the challenges encountered in biological research because a large number of small samples can be handled and processed with different functional elements in an automated fashion.
Revised: July 28, 2014 |
Published: July 1, 2014
Citation
Sun X., and R.T. Kelly. 2014.Biological Sample Preparation and Analysis Using Droplet-Based Microfluidics. In Nanopatterning and Nanoscale Devices for Biological Applications, edited by S Selimovic. 73-92. Boca Raton, Florida:CRC Press.PNNL-SA-104090.