Here we report the atomic-scale analysis of biological interfaces using atom probe tomography. Embedding the protein ferritin in an organic polymer resin lacking nitrogen provided chemical contrast to visualize atomic distributions and distinguish organic-organic and organic-inorganic interfaces. The sample preparation method can be directly extended to further enhance the study of biological, organic and inorganic nanomaterials relevant to health, energy or the environment.
Revised: June 23, 2020 |
Published: February 29, 2016
Citation
Perea D.E., J. Liu, J. Bartrand, Q.G. Dicken, S. Thevuthasan, N.D. Browning, and J.E. Evans. 2016.Atom Probe Tomographic Mapping Directly Reveals the Atomic Distribution of Phosphorus in Resin Embedded Ferritin.Scientific Reports 6.PNNL-SA-112512.doi:10.1038/srep22321