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Young-Mo

Young-Mo Kim

Engage & Perform
Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: K8-98
Richland, WA 99352

Biography

Dr. Young-Mo Kim is an analytical chemist who explores various metabolites from complex environmental samples. He got his Ph.D. degree in environmental analytical chemistry at the School of Environmental Science and Engineering, Pohang University of Science and Technology (POSTECH) in South Korea. Then, he joined Dick Smith Group in PNNL and spent his post-doctoral training period for metabolomics research under the mentorship of Drs. Thomas Metz and Qibin Zhang. He has been using separation technologies such as gas chromatography and liquid chromatography, coupled with various types of mass spectrometers to accurately measure small organic molecules (e.g. metabolites). He is actively working on several projects funded by DOE, NIH and EMSL which require successful measurements of global metabolome changes in given biological/environmental systems. Generation of high-throughput metabolomics data and following validations are his priorities in those projects. In addition, he is participating in a project for the development of new metabolomics platform, ion mobility spectrometry in conjunction with mass spectrometry (IMS-MS) for better separation and detection of metabolites.

Research Interests

  • Metabolomics / Lipidomics
  • Chromatography / Mass Spectrometry
  • Environmental Chemistry
  • Environmental Microbiology

Education and Credentials

  • Pacific Northwest National Laboratory, Post-Doctoral, Metabolomics, 2012
  • POSTECH, PhD, Environmental Analytical Chemistry, 2009
  • Sungkyunkwan University, BS, Genetic Engineering, 2000

Affiliations and Professional Service

  • American Society for Mass Spectrometry
  • American Society for Microbiology

PNNL Publications

2014

  • Anderson JC, Y Wan, YM Kim, L Pasa-Tolic, TO Metz, and SC Peck. 2014. "Decreased abundance of type III secretion system-inducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae." Proceedings of the National Academy of Sciences of the United States of America 111(18):6846-6851.  doi:10.1073/pnas.1403248111
  • Cole JK, JR Hutchison, RS Renslow, YM Kim, WB Chrisler, HE Engelmann, A Dohnalkova, D Hu, TO Metz, JK Fredrickson, and SR Lindemann. 2014. "Phototrophic Biofilm Assembly in Microbial-Mat-Derived Unicyanobacterial Consortia: Model Systems for the Study of Autotroph-Heterotroph Interactions." Frontiers in Microbiology 5:Article No. 109.  doi:10.3389/fmicb.2014.00109
  • Webb-Robertson BJM, YM Kim, EM Zink, KA Hallaian, Q Zhang, R Madupu, KM Waters, and TO Metz. 2014. "A Statistical Analysis of the Effects of Urease Pre-Treatment on the Measurement of the Urinary Metabolome by Gas Chromatography-Mass Spectrometry." Metabolomics 1(12):, doi:10.1007/s11306-014-0642-1

2013

  • Kim YM, B Schmidt, AS Kidwai, MB Jones, BL Deatherage, HM Brewer, HD Mitchell, BO Palsson, JE McDermott, F Heffron, RD Smith, SN Peterson, C Ansong, DR Hyduke, TO Metz, and JN Adkins. 2013. "Salmonella Modulates Metabolism During Growth under Conditions that Induce Expression of Virulence Genes." Molecular Biosystems 9(6):1522-1534.  doi:10.1039/C3MB25598K
  • Ansong C, AC Rutledge, HD Mitchell, S Chauhan, MB Jones, YM Kim, K Mcateer, BL Deatherage, JL DuBois, HM Brewer, BC Frank, JE McDermott, TO Metz, SN Peterson, RD Smith, VL Motin, and JN Adkins. 2013. "A multi-omic systems approach to elucidating Yersinia virulence mechanisms." Molecular Biosystems 9(1):44-54.  doi:10.1039/C2MB25287B
  • Kaiser BLD, J Li, JA Sanford, YM Kim, SR Kronewitter, MB Jones, C Peterson, SN Peterson, BC Frank, SO Purvine, JN Brown, TO Metz, RD Smith, F Heffron, and JN Adkins. 2013. "A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection." PLoS One 8(6):Article No. e67155.  doi:10.1371/journal.pone.0067155

2012

  • Bordbar A, ML Mo, ES Nakayasu, AC Rutledge, YM Kim, TO Metz, MB Jones, BC Frank, RD Smith, SN Peterson, DR Hyduke, JN Adkins, and BO Palsson. 2012. "Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation." Molecular Systems Biology 8:Article No. 558.  doi:10.1038/msb.2012.21
  • Hu Z, YM Kim, MB Sowa, RJ Robinson, X Gao, TO Metz, WF Morgan, and Q Zhang. 2012. "Metabolomic Response of Human Skin Tissue to Low Dose Ionizing Radiation." Molecular Biosystems 8(7):1979-1986.  doi:10.1039/C2MB25061F

2011

  • Kim YM, TO Metz, Z Hu, SD Wiedner, JS Kim, RD Smith, WF Morgan, and Q Zhang. 2011. "Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics ." Rapid Communications in Mass Spectrometry 25:2561-2564.  doi:10.1002/rcm.5134

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