Staff information

PNNL Publications

2025

• Zemaitis K., J.M. Fulcher, R. Kumar, D.J. Degnan, L.A. Lewis, Y. Liao, and M. Velickovic, et al. 2025. "Spatial top-down proteomics for the functional characterization of human kidney." Clinical Proteomics 22:Art. No. 9. PNNL-SA-193767. doi:10.1186/s12014-025-09531-x

2024

• Fulcher J.M., L. Markillie, H.D. Mitchell, S.M. Williams, K.M. Engbrecht, D.J. Degnan, and L.M. Bramer, et al. 2024. "Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting." Nature Communications 15, no. _:Art. No. 10614. PNNL-SA-205430. doi:10.1038/s41467-024-54099-z
• Kumar R., K. Zemaitis, J.M. Fulcher, and L. Pasa-Tolic. 2024. "Advances in mass spectrometry-enabled multiomics analyses at single-cell resolution." Current Opinion in Biotechnology 87. PNNL-SA-194867. doi:10.1016/j.copbio.2024.103096
• Kwon Y., J.M. Fulcher, L. Pasa-Tolic, and W. Qian. 2024. "Spatial Proteomics towards Cellular Resolution." Expert Review of Proteomics 21, no. 12:505 - 514. PNNL-SA-203070. doi:10.1080/14789450.2024.2445809

2023

• Chen Y., A.J. Taylor, J.M. Fulcher, A.C. Swensen, X. Dai, M. Komba, and K.L. Wrightson, et al. 2023. "Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice." Diabetes 72, no. 9:1277-1288. PNNL-SA-186901. doi:10.2337/db22-0945
• Degnan D.J., K. Zemaitis, L.A. Lewis, L. McCue, L.M. Bramer, J.M. Fulcher, and D. Velickovic, et al. 2023. "IsoMatchMS: Open-Source Software for Automated Annotation and Visualization of High Resolution MALDI-MS Spectra." Journal of the American Society for Mass Spectrometry 34, no. 9:2061-2064. PNNL-SA-184623. doi:10.1021/jasms.3c00180
• Fulcher J.M., A.C. Swensen, Y. Chen, B. Verchere, V.A. Petyuk, and W. Qian. 2023. "Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing." Endocrinology 164, no. 12:Art. No. bqad160. PNNL-SA-188096. doi:10.1210/endocr/bqad160
• Fulcher J.M., L. Markillie, H.D. Mitchell, S.M. Williams, K.M. Engbrecht, R.J. Moore, and W.B. Chrisler, et al. 2023. Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting. PNNL-34730. Richland, WA: Pacific Northwest National Laboratory. Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting
• Liao Y., J.M. Fulcher, D.J. Degnan, S.M. Williams, L.M. Bramer, D. Velickovic, and K. Zemaitis, et al. 2023. "Spatially resolved top-down proteomics of tissue sections based on a microfluidic nanodroplet sample preparation platform." Molecular & Cellular Proteomics 22, no. 2:Art. No. 100491. PNNL-SA-174522. doi:10.1016/j.mcpro.2022.100491
• Martin E.A., J.M. Fulcher, M. Zhou, M.E. Monroe, and V.A. Petyuk. 2023. "TopPICR: a companion R package for top-down proteomics data analysis." Journal of Proteome Research 22, no. 2:399-409. PNNL-SA-177756. doi:10.1021/acs.jproteome.2c00570
• Park J., F. Yu, J.M. Fulcher, S.M. Williams, K.M. Engbrecht, R.J. Moore, and G. Clair, et al. 2023. "Evaluating linear ion trap for MS3-based multiplexed single-cell proteomics." Analytical Chemistry 95, no. 3:1888-1898. PNNL-SA-176981. doi:10.1021/acs.analchem.2c03739