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Fundamental and Computational Sciences Directorate

Staff information

Nikola Tolic

Scientific & Computing Operations
Pacific Northwest National Laboratory
PO Box 999
MSIN: K8-91
Richland, WA 99352

PNNL Publications


  • Blair SL, AC Macmillan, GT Drozd, AH Goldstein, RK Chu, L Pasa Tolic, JB Shaw, N Tolic, P Lin, J Laskin, A Laskin, and S Nizkorodov. 2017. "Molecular Characterization of Organosulfur Compounds in Biodiesel and Diesel Fuel Secondary Organic Aerosol." Environmental Science & Technology 51(1):119-127.  doi:10.1021/acs.est.6b03304
  • Chen H, RC Johnston, BF Mann, RK Chu, N Tolic, JM Parks, and B Gu. 2017. "Identification of Mercury and Dissolved Organic Matter Complexes Using Ultrahigh Resolution Mass Spectrometry." Environmental Science & Technology Letters 4(2):59-65.  doi:10.1021/acs.estlett.6b00460
  • Kou Q, S Wu, N Tolic, L Pasa Tolic, Y Liu, and X Liu. 2017. "A mass graph-based approach for the identification of modified proteoforms using top-down tandem mass spectra." Bioinformatics 33(9):1309-1316.  doi:10.1093/bioinformatics/btw806
  • Park JK, PD Piehowski, CS Wilkins, M Zhou, JA Mendoza, GM Fujimoto, BC Gibbons, JB Shaw, Y Shen, AK Shukla, RJ Moore, T Liu, VA Petyuk, N Tolic, L Pasa Tolic, RD Smith, SH Payne, and S Kim. 2017. "Informed-Proteomics: Open Source Software Package for Top-down Proteomics." Nature Methods 14(9):909-914.  doi:10.1038/nmeth.4388
  • Shen Y, N Tolic, PD Piehowski, AK Shukla, S Kim, R Zhao, Y Qu, EW Robinson, RD Smith, and L Pasa-Tolic. 2017. "High-resolution ultrahigh-pressure long column reversed-phase liquid chromatography for top-down proteomics." Journal of Chromatography A 1498:99-110.  doi:10.1016/j.chroma.2017.01.008
  • Shen Y, N Tolic, PD Piehowski, AK Shukla, S Kim, R Zhao, Y Qu, EW Robinson, RD Smith, and L Pasa-Tolic. 2017. "High-Resolution Ultrahigh-PressurePhase Liquid Chromatography for To Long Column Reversed-p-Down Proteomics." Journal of Chromatography A 1498:99-110.  doi:10.1016/j.chroma.2017.01.008
  • Tfaily MM, RK Chu, JG Toyoda, N Tolic, EW Robinson, L Pasa Tolic, and NJ Hess. 2017. "Sequential extraction protocol for organic matter from soils and sediments using high resolution mass spectrometry." Analytica Chimica Acta 972:54-61.  doi:10.1016/j.aca.2017.03.031


  • Shaw JB, TY Lin, FE Leach, III, AV Tolmachev, N Tolic, EW Robinson, DW Koppenaal, and L Pasa Tolic. 2016. "21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Greatly Expands Mass Spectrometry Toolbox." Journal of the American Society for Mass Spectrometry 27(12):1929-1936.  doi:10.1007/s13361-016-1507-9
  • Anderton CR, RK Chu, N Tolic, AV Creissen, and L Pasa-Tolic. 2016. "Utilizing a Robotic Sprayer for High Lateral and Mass Resolution MALDI FT-ICR MSI of Microbial Cultures." Journal of the American Society for Mass Spectrometry 27(3):556-559.  doi:10.1007/s13361-015-1324-6
  • Kaplan DI, C Xu, S Huang, Y Lin, N Tolic, KM Roscioli, PH Santschi, and PR Jaffe. 2016. "Unique Organic Matter and Microbial Properties in the Rhizosphere of a Wetland Soil." Environmental Science & Technology 50(8):4169-4177.  doi:10.1021/acs.est.5b05165
  • Kou Q, B Zhu, S Wu, CK Ansong, N Tolic, L Pasa Tolic, and X Liu. 2016. "Characterization of Proteoforms with Unknown Post-translational Modifications Using the MIScore." Journal of Proteome Research 15(8):2422-2432.  doi:10.1021/acs.jproteome.5b01098
  • Sun J, T Dutta, R Parthasarathi, KH Kim, N Tolic, RK Chu, NG Isern, JR Cort, BA Simmons, and S Singh. 2016. "Rapid room temperature solubilization and depolymerization of polymeric lignin at high loadings." Green Chemistry 18(22):6012-6020.  doi:10.1039/C6GC02258H
  • Vyatkina K, S Wu, LJ Dekker, MM vanDuijn, X Liu, N Tolic, TM Luider, L Pasa Tolic, and PA Pevzner. 2016. "Top-down analysis of protein samples by de novo sequencing techniques." Bioinformatics 32(18):2753-2759.  doi:10.1093/bioinformatics/btw307


  • Mann BF, HM Chen, EM Herndon, RK Chu, N Tolic, E Portier, TR Chowdhury, EW Robinson, SJ Callister, SD Wullschleger, DE Graham, L Liang, and B Gu. 2015. "Indexing Permafrost Soil Organic Matter Degradation Using High-Resolution Mass Spectrometry." PLoS One 10(6):Article No. e0130557.  doi:10.1371/journal.pone.0130557
  • Tfaily MM, RK Chu, N Tolic, KM Roscioli, CR Anderton, L Pasa-Tolic, EW Robinson, and NJ Hess. 2015. "Advanced solvent based methods for molecular characterization of soil organic matter by high-resolution mass spectrometry." Analytical Chemistry 87(10):5206-5215.  doi:10.1021/acs.analchem.5b00116
  • Vyatkina K, S Wu, LJ Dekker, MM vanDuijn, X Liu, N Tolic, M Dvorkin, S Alexandrova, TN Luider, L Pasa-Tolic, and PA Pevzner. 2015. "De novo sequencing of peptides from top-down tandem mass spectra." Journal of Proteome Research 14(11):4450-4462.  doi:10.1021/pr501244v
  • Xu Z, C Wu, F Xie, GW Slysz, N Tolic, ME Monroe, VA Petyuk, SH Payne, GM Fujimoto, RJ Moore, TL Fillmore, AA Schepmoes, D Levine, R Townsend, S Davies, S Li, M Ellis, E Boja, R Rivers, H Rodriguez, KD Rodland, T Liu, and RD Smith. 2015. "Comprehensive Quantitative Analysis of Ovarian and Breast Cancer Tumor Peptidomes." Journal of Proteome Research 14(1):422-433.  doi:10.1021/pr500840w
  • Xu Z, C Wu, F Xie, GW Slysz, N Tolic, ME Monroe, VA Petyuk, SH Payne, GM Fujimoto, RJ Moore, TL Fillmore, AA Schepmoes, D Levine, R Townsend, S Davies, S Li, M Ellis, E Boja, R Rivers, H Rodriguez, KD Rodland, T Liu, and RD Smith. 2015. "Comprehensive Quantitative Analysis of Ovarian and Breast Cancer Tumor Peptidomes." Journal of Proteome Research 14(1):422-433.  doi:10.1021/pr500840w


  • Cao L, N Tolic, Y Qu, D Meng, R Zhao, Q Zhang, RJ Moore, EM Zink, MS Lipton, L Pasa-Tolic, and S Wu. 2014. "Characterization of intact N- and O-linked glycopeptides using higher energy collisional dissociation." Analytical Biochemistry 452:96-102.  doi:10.1016/j.ab.2014.01.003
  • Dang X, J Scotcher, S Wu, RK Chu, N Tolic, I Ntai, P Thomas, RT Fellers , BP Early, Y Zheng, KR Durbin, RD LeDuc, JJ Wolff, CJ Thompson, J Pan, J Han, JB Shaw, JP Salisbury, M Easterling, CH Borchers, JS Brodbelt, J Agar, L Pasa-Tolic, N Kelleher, and NL Young. 2014. "The first pilot project of the consortium for top-down proteomics: A status report." Proteomics 14(10):1130-1140.  doi:10.1002/pmic.201300438
  • Dekker LJ, S Wu, MM vanDuijn, N Tolic, C Stingl, R Zhao, TN Luider, and L Pasa-Tolic. 2014. "An integrated top-down and bottom-up proteomic approach to characterize the antigen binding fragment of antibodies." Proteomics 14(10):1239-1248.  doi:10.1002/pmic.201300366
  • Wu S, JN Brown, N Tolic, D Meng, X Liu, H Zhang, R Zhao, RJ Moore, PA Pevzner, RD Smith, and L Pasa-Tolic. 2014. "Quantitative Analysis of Human Salivary Gland-Derived Intact Proteome Using Top-Down Mass Spectrometry." Proteomics 14(10):1211-1222.  doi:10.1002/pmic.201300378


  • Halim MF, F Pfeiffer, J Zou, A Frisch, DH Haft, S Wu, N Tolic, HM Brewer, SH Payne, L Pasa-Tolic, and M Pohlschroder. 2013. "Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein." Molecular Microbiology 88(6):1164-1175.  doi: 10.1111/mmi.12248
  • Liu X, SM Hengel, S Wu, N Tolic, L Pasa-Tolic, and PA Pevzner. 2013. "Identification of Ultramodified Proteins Using Top-Down Mass Spectra." Journal of Proteome Research 12(12):5830-8.  doi:10.1021/pr400849y
  • Liu X, SM Hengel, S Wu, N Tolic, L Pasa-Tolic, and PA Pevzner. 2013. "Identification of ultramodified proteins using top-down spectra." In Research in Computational Molecular Biology: 17th Annual International Conference, April 7-10, 2013, Beijing, China. Lecture Notes in Computer Science, vol. 7821, ed. M Deng, et al, pp. 132-144.  Springer , Berlin, Germany.  doi:10.1007/978-3-642-37195-0_11
  • Wu S, RN Brown, SH Payne, D Meng, R Zhao, N Tolic, L Cao, AK Shukla, ME Monroe, RJ Moore, MS Lipton, and L Pasa-Tolic. 2013. "Top-down characterization of the post-translationally modified intact periplasmic proteome of the bacterium Novosphingobium aromaticivorans ." International Journal of Proteomics 2013:279590.  doi:10.1155/2013/279590


  • Shen Y, N Tolic, SO Purvine, and RD Smith. 2012. "Improving Collision Induced Dissociation (CID), High Energy Collision Dissociation (HCD), and Electron Transfer Dissociation (ETD) Fourier Transform MS/MS Degradome-Peptidome Identifications Using High Accuracy Mass Information." Journal of Proteome Research 11(2):668-677. 
  • Tian Z, N Tolic, R Zhao, RJ Moore, SM Hengel, EW Robinson, DL Stenoien, S Wu, RD Smith, and L Pasa-Tolic. 2012. "Enhanced top-down characterization of histone post-translational modifications ." Genome Biology 13(10):R86.  doi:10.1186/gb-2012-13-10-r86


  • Lopez-Ferrer D, K Petritis, EW Robinson, KK Hixson, Z Tian, JH Lee, SW Lee, N Tolic, KK Weitz, ME Belov, RD Smith, and L Pasa-Tolic. 2011. "Pressurized Pepsin Digestion in Proteomics: An Automatable Alternative to Trypsin for Integrated Top-down Bottom-up Proteomics." Molecular & Cellular Proteomics. MCP 10(2):, doi:10.1074/mcp.M110.001479
  • Ansong C, N Tolic, SO Purvine, S Porwollik, MB Jones, H Yoon, SH Payne, JL Martin, MC Burnet, ME Monroe, P Venepally, RD Smith, S Peterson, F Heffron, M Mcclelland, and JN Adkins. 2011. "Experimental annotation of post-translational features and translated coding regions in the pathogen Salmonella Typhimurium." BMC Genomics 12:Art. No. 433.  doi:10.1186/1471-2164-12-433
  • Shen Y, N Tolic, SO Purvine, and RD Smith. 2011. "Improving CID, HCD, and ETD FT MS/MS degradome-peptidome identifications using high accuracy mass information." Journal of Proteome Research doi:10.1021/pr200597j
  • Shen Y, N Tolic, F Xie, R Zhao, SO Purvine, AA Schepmoes, RJ Moore, GA Anderson, and RD Smith. 2011. "Effectiveness of CID, HCD, and ETD with FT MS/MS for degradomic-peptidomic analysis: comparison of peptide identification methods." Journal of Proteome Research 10(9):3929-3943.  doi:10.1021/pr200052c
  • Wu S, N Tolic, Z Tian, EW Robinson, and L Pasa-Tolic. 2011. "An integrated top-down and bottom-up strategy for characterization protein isoforms and modifications." Chapter 18 in Bioinformatics for Comparative Proteomics: Methods in Molecular Biology, vol. 694, ed. CH Wu and C Chen, pp. 291-304.  Springer, New York, NY. 


  • Jung HJ, SO Purvine, H Kim, VA Petyuk, SW Hyung, ME Monroe, DG Mun, KC Kim, JM Park, SJ Kim, N Tolic, GW Slysz, RJ Moore, R Zhao, JN Adkins, GA Anderson, H Lee, DG Camp, II, MH Yu, RD Smith, and SW Lee. 2010. "Integrated Post-Experiment Monoisotopic Mass Refinement: An Integrated Approach to Accurately Assign Monoisotopic Precursor Masses to Tandem Mass Spectrometric Data." Analytical Chemistry 82(20):8510-8518.  doi:10.1021/ac101388b
  • Shen Y, N Tolic, SO Purvine, and RD Smith. 2010. "Identification of Disulfide Bonds in Protein Proteolytic Degradation Products Using de Novo-Protein Unique Sequence Tags Approach." Journal of Proteome Research 9(8):4053-4060. 
  • Shen Y, N Tolic, T Liu, R Zhao, BO Petritis, MA Gritsenko, DG Camp, II, RJ Moore, SO Purvine, FJ Esteva, and RD Smith. 2010. " Blood Peptidome-Degradome Profile of Breast Cancer." PLoS One 5(10):Article No.: e13133.  doi:10.1371/journal.pone.0013133
  • Shen Y, T Liu, N Tolic, BO Petritis, R Zhao, RJ Moore, SO Purvine, DG Camp, II, and RD Smith. 2010. "A strategy for degradomic-peptidomic analysis of the human blood plasma ." Journal of Proteome Research 9(5):2339-2346.  doi:10.1021/pr901083m
  • Tian Z, R Zhao, N Tolic, RJ Moore, DL Stenoien, EW Robinson, RD Smith, and L Pasa-Tolic. 2010. "Two-dimensional liquid chromatography system for online top-down mass spectrometry." Proteomics 10(20):3610-3620.  doi:10.1002/pmic.201000367


  • Yang F, S Wu, DL Stenoien, R Zhao, ME Monroe, MA Gritsenko, SO Purvine, AD Polpitiya, N Tolic, Q Zhang, AD Norbeck, DJ Orton, RJ Moore, K Tang, GA Anderson, L Pasa-Tolic, DG Camp, II, and RD Smith. 2009. "Combined Pulsed-Q dissociation and electron transfer dissociation for identification and quantitation of iTRAQ-labeled phosphopeptides." Analytical Chemistry 81(10):4137-4143.  doi:10.1021/ac802605m
  • Chowdhury SM, X Du, N Tolic, S Wu, RJ Moore, MU Mayer, RD Smith, and JN Adkins. 2009. "Identification of Cross-Linked Peptides after Click-Based Enrichment Using Sequential Collision-Induced Dissociation and Electron Transfer Dissociation Tandem Mass Spectrometry." Analytical Chemistry 81(13):5524-5532.  doi:10.1021/ac900853k
  • Wu S, F Yang, R Zhao, N Tolic, EW Robinson, DG Camp, II, RD Smith, and L Pasa-Tolic. 2009. "An integrated workflow for characterizing intact phosphoproteins from complex mixtures." Analytical Chemistry 81(11):4210-4219.  doi:10.1021/ac802487q
  • Wu S, NM Lourette, N Tolic, R Zhao, R Robinson, AV Tolmachev, RD Smith, and L Pasa-Tolic. 2009. "An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications." Journal of Proteome Research 8(3):1347-1357. 
  • Zhang H, X Tang, GR Munske, N Tolic, GA Anderson, and JE Bruce. 2009. "Identification of Protein-Protein Interactions and Topologies in Living Cells with Chemical Cross-linking and Mass Spectrometry." Molecular & Cellular Proteomics. MCP 8(3):409-420. 


  • Shen Y, KK Hixson, N Tolic, DG Camp, II, SO Purvine, RJ Moore, and RD Smith. 2008. "Mass Spectrometry Analysis of Proteome-wide Proteolytic Post-translational Degradation of Proteins." Analytical Chemistry 80(15):5819-5828.  doi:10.1021/ac800077w
  • Shen Y, N Tolic, KK Hixson, SO Purvine, GA Anderson, and RD Smith. 2008. "De novo sequencing of unique sequence tags for discovery of post-translational modifications of proteins ." Analytical Chemistry 80(20):7742-7754.  doi:10.1021/ac801123p
  • Shen Y, N Tolic, KK Hixson, SO Purvine, L Pasa-Tolic, W Qian, JN Adkins, RJ Moore, and RD Smith. 2008. "Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags." Analytical Chemistry 80(6):1871-82.  doi:10.1021/ac702328x
  • Zhang H, X Tang, GR Munske, N Tolic, GA Anderson, and JE Bruce. 2008. "Identification of protein-protein interaction and topologies in living cells by chemical cross-linking and mass spectrometry." Molecular & Cellular Proteomics. MCP 8(3):409-420.  doi:10.1074/mcp.M800232-MCP200
  • Zhang H, X Tang, GR Munske, NL Zakharova, L Yang, C Zheng, MA Wolff, N Tolic, GA Anderson, L Shi, MJ Marshall, JK Fredrickson, and JE Bruce. 2008. "In Vivo Identification of the Outer Membrane Protein OmcA-MtrC Interaction Network in Shewanella oneidensis MR-1 Cells Using Novel Hydrophobic Chemical Cross-Linkers." Journal of Proteome Research 7(4):1712-1720.  doi:10.1021/pr7007658


  • Sharma S, DC Simpson, N Tolic, N Jaitly, AM Mayampurath, RD Smith, and L Pasa-Tolic. 2007. "Proteomic profiling of intact proteins using WAX-RPLC 2-D separations and FTICR mass spectrometry." Journal of Proteome Research 6(2):602-610.  doi:10.1021/pr060354a
  • Anderson GA, N Tolic, X Tang, C Zheng, and JE Bruce. 2007. "Informatics Strategies for Large-Scale Novel Cross-linking Analysis ." Journal of Proteome Research 6(9):3412-3421.  doi:10.1021/pr070035z
  • Anderson GA, N Tolic, X Tang, C Zheng, and JE Bruce. 2007. "Informatics Strategies for Large-Scale Novel Cross-linking Analysis." Journal of Proteome Research 6(9):3412-3421.  doi:10.1021/pr070035z
  • Monroe ME, N Tolic, N Jaitly, JL Shaw, JN Adkins, and RD Smith. 2007. "VIPER: an advanced software package to support high-throughput LC-MS peptide identification." Bioinformatics 23(15- August 2007):2021-2023.  doi:10.1093/bioinformatics/btm281


  • Elshafey A, N Tolic, MM Young, KL Sale, RD Smith, and V Kery. 2006. "“Zero-length” Cross-linking in Solid State as an Approach for Analysis of Protein -Protein Interactions." Protein Science 15(3):429-440. 
  • Kiebel GR, KJ Auberry, N Jaitly, D Clark, ME Monroe, ES Peterson, N Tolic, GA Anderson, and RD Smith. 2006. "PRISM: A Data Management System for High-Throughput Proteomics ." Proteomics 6(6):1783-1790.  doi:10.1002/pmic.200500500
  • Lipton MS, MF Romine, ME Monroe, DA Elias, L Pasa-Tolic, GA Anderson, DJ Anderson, JK Fredrickson, KK Hixson, CD Masselon, HM Mottaz, N Tolic, and RD Smith. 2006. "AMT Tag Approach to Proteomic Characterization of Deinococcus Radiodurans and Shewanella Oneidensis ." In Microbial Proteomics, Methods of Biochemical Analysis, vol. 49, ed. I. Humphery-Smith and M. Hecker, pp. 113-134.  John Wiley & Sons, Inc., Hoboken, NJ. 


  • Masselon CD, L Pasa-Tolic, N Tolic, GA Anderson, B Bogdanov, AN Vilkov, Y Shen, R Zhao, W Qian, MS Lipton, DG Camp, II, and RD Smith. 2005. "Targeted Comparative Proteomics by Liquid Chromatography - Tandem Fourier ion cyclotron resonance Mass Spectrometry." Analytical Chemistry 77(2):400-406. 
  • Shen Y, J Kim, EF Strittmatter, JM Jacobs, DG Camp, II, R Fang, N Tolic, RJ Moore, and RD Smith. 2005. "Characterization of the human blood plasma proteome." Proteomics 5(15):4034-4045. 


  • Shen Y, N Tolic, CD Masselon, L Pasa-Tolic, DG Camp, II, GA Anderson, RD Smith, and MS Lipton. 2004. "Nanoscale Proteomics." Analytical and Bioanalytical Chemistry 378(4):1037-1045. 
  • Shen Y, N Tolic, CD Masselon, L Pasa-Tolic, DG Camp, II, KK Hixson, R Zhao, GA Anderson, and RD Smith. 2004. "Ultrasensitive Proteomics using High-Efficiency on-Line Micro-SPE-NanoLC-NanoESI MS and MS/MS." Analytical Chemistry 76(1):144-154. 


  • Mohan D, L Pasa-Tolic, CD Masselon, N Tolic, B Bogdanov, KK Hixson, RD Smith, and CS Lee. 2003. "Integration of Electrokinetic-Based Multidimensional Separations/Concentration Platform with electrospray ionization-Fourier transform ion cyclotron resonance-mass spectrometry for Proteome Analysis of Shewanella Oneidensis." Analytical Chemistry 75(17):4432-4440. 


  • Berger SJ, SW Lee, GA Anderson, L Pasa-Tolic, N Tolic, Y Shen, R Zhao, and RD Smith. 2002. "High-Throughput Global Peptide Proteomic Analysis by Combining Stable Isotope Amino Acid Labeling and Data-Dependent Multiplexed-MS/MS." Analytical Chemistry 74(19):4994-5000. 
  • Lipton MS, L Pasa-Tolic, GA Anderson, DJ Anderson, DL Auberry, JR Battista, MJ Daly, JK Fredrickson, KK Hixson, HM Kostandarithes, CD Masselon, LM Markillie, RJ Moore, MF Romine, Y Shen, EF Strittmatter, N Tolic, HR Udseth, A Venkateswaran, KK Wong, R Zhao, and RD Smith. 2002. "Global Analysis of Deinococcus Radiodurans Proteome by Csing Accurate Mass Tags." Proceedings of the National Academy of Sciences of the United States of America 99(17):11049-11054. 
  • Pasa-Tolic L, MS Lipton, CD Masselon, GA Anderson, Y Shen, N Tolic, and RD Smith. 2002. "Gene expression profiling using advanced mass spectrometric approaches." Journal of Mass Spectrometry 37(12):1185-1198. 
  • Pasa-Tolic L, R Harkewicz, GA Anderson, N Tolic, Y Shen, R Zhao, BD Thrall, CD Masselon, and RD Smith. 2002. "Increased Proteome Coverage for Quantitative Peptide Abundance Measurements Based upon High Performance Separations and DREAMS FTICR Mass Spectrometry." Journal of the American Society for Mass Spectrometry 13(8):954-963. 


  • Belov ME, GA Anderson, NH Angell, Y Shen, N Tolic, HR Udseth, and RD Smith. 2001. "Dynamic Range Expansion Applied to Mass Spectrometry (DREAMS) Based on Data-Dependent Selective Ion Ejection in Capillary Liquid Chromatography Fourier Transform Ion Cyclotron Resonance for Enhanced Proteome Characterization." Analytical Chemistry 73(21):5052-5060. 
  • Li L, CD Masselon, GA Anderson, L Pasa-Tolic, SW Lee, Y Shen, R Zhao, MS Lipton, TP Conrads, N Tolic, and RD Smith. 2001. "High-Throughput Peptide Identification from Protein Digests Using Data-Dependent Multiplexed Tandem FTICR Mass Spectrometry Coupled with Capillary Liquid Chromatography." Analytical Chemistry 73(14):3312-3322. 
  • Shen Y, N Tolic, R Zhao, L Pasa-Tolic, L Li, SJ Berger, R Harkewicz, GA Anderson, ME Belov, and RD Smith. 2001. "High-Throughput Proteomics Using High Efficiency Multiple-Capillary Liquid Chromatography With On-Line High-Performance ESI FTICR Mass Spectrometry." Analytical Chemistry 73(13):3011-3021. 


  • Jensen PK, L Pasa-Tolic, KK Peden, S Martinovic, MS Lipton, GA Anderson, N Tolic, KK Wong, and RD Smith. 2000. "Mass Spectrometric Detection for Capillary Isoelectric Focusing Separations of Complex Protein Mixtures." Electrophoresis 21(7):1372-1380. 


  • Pasa-Tolic L, PK Jensen, GA Anderson, MS Lipton, KK Peden, S Martinovic, N Tolic, JE Bruce, and RD Smith. 1999. "High Throughput Proteome-Wide Precision Measurements of Protein Expression using Mass Spectrometry." Journal of the American Chemical Society 121(34):7949-7950. 

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