Staff information

PNNL Publications

2024

• Gaither K.A., W.L. Garcia, K.J. Tyrrell, A.T. Wright, and J.N. Smith. 2024. "Activity-based protein profiling to probe relationships between cytochrome P450 enzymes and early-age metabolism of two polycyclic aromatic hydrocarbons (PAHs): phenanthrene and retene." Chemical Research in Toxicology 37, no. 5:711-722. PNNL-SA-193633. doi:10.1021/acs.chemrestox.3c00424
• Schultz K.J., J.H. Nguyen, V.S. Lin, C. Kombala Nanayakkara Thambiliya, K.J. Tyrrell, and P.M. Lalli. 2024. Heracles: Predictive Tools for Opioid Crisis Intervention - m/q Initiative Project Report. PNNL-36739. Richland, WA: Pacific Northwest National Laboratory. Heracles: Predictive Tools for Opioid Crisis Intervention - m/q Initiative Project Report

2021

• Brandvold K.R., S.P. Couvillion, T.M. Gibbins, and K.J. Tyrrell. 2021. Illuminating gut microbiome signaling pathways that regulate host circadian rhythms. PNNL-32131. Richland, WA: Pacific Northwest National Laboratory. Illuminating gut microbiome signaling pathways that regulate host circadian rhythms
• Plymale A.E., J.R. Wells, C.I. Pearce, C.J. Brislawn, E.B. Graham, T. Cheeke, and J.L. Allen, et al. 2021. "Niche partitioning of microbial communities at an ancient vitrified hillfort: implications for vitrified radioactive waste disposal." Geomicrobiology Journal 38, no. 1:36-56. PNNL-SA-150253. doi:10.1080/01490451.2020.1807658
• Stoddard E.G., S. Nag, J. Martin, K.J. Tyrrell, T.M. Gibbins, K.A. Anderson, and A.K. Shukla, et al. 2021. "Exposure to an environmental mixture of polycyclic aromatic hydrocarbons induces hepatic cytochrome P450 enzymes in mice." Chemical Research in Toxicology 34, no. 9:2145 - 2156. PNNL-SA-163871. doi:10.1021/acs.chemrestox.1c00235

2020

• Nelson W.C., L.N. Anderson, R. Wu, J.E. McDermott, S.L. Bell, A. Jumpponen, and S.J. Fansler, et al. 2020. "Terabase Metagenome Sequencing of Grassland Soil Microbiomes." Microbiology Resource Announcements 9, no. 32:Article No. e00718-20. PNNL-SA-153752. doi:10.1128/MRA.00718-20
• Smith J.N., K.J. Tyrrell, J.P. Smith, J.P. Smith, K.K. Weitz, and W.D. Faber. 2020. "Linking Internal Dosimetries of the Propyl Metabolic Series in Rats and Humans Using Physiologically Based Pharmacokinetic (PBPK) Modeling." Regulatory Toxicology and Pharmacology 110. PNNL-ACT-SA-10429. doi:10.1016/j.yrtph.2019.104507
• Sveistyte A., T.M. Gibbins, K.J. Tyrrell, C.J. Miller, M.H. Foley, A.E. Plymale, and A.T. Wright, et al. 2020. "Simple analysis of primary and secondary bile salt hydrolysis in mouse and human gut microbiome samples using fluorogenic substrates." Chembiochem 21, no. 24:3539-3543. PNNL-SA-152472. doi:10.1002/cbic.202000370

2019

• Han A., C. Timchalk, Z.A. Carver, T.J. Weber, K.J. Tyrrell, R.L. Sontag, and T.M. Gibbins, et al. 2019. "Physiologically based pharmacokinetic modeling of salivary concentrations for noninvasive biomonitoring of 2,4-dichlorophenoxyacetic acid (2,4-D)." Toxicological Sciences 171, no. 2:330-343. PNNL-SA-143610. doi:10.1093/toxsci/kfz206

2018

• Carver Z.A., A. Han, C. Timchalk, T.J. Weber, K.J. Tyrrell, R.L. Sontag, and T. Luders, et al. 2018. "Evaluation of Non-invasive Biomonitoring of 2,4-Dichlorophenoxyacetic Acid (2,4-D) in Saliva." Toxicology 410. PNNL-SA-135310. doi:10.1016/j.tox.2018.08.003

2017

• Smith J.N., K.J. Tyrrell, J.R. Hansen, D.G. Thomas, T.A. Murphree, A.K. Shukla, and T. Luders, et al. 2017. "Plasma Protein Turnover Rates in Rats Using Stable Isotope Labeling, Global Proteomics, and Activity-Based Protein Profiling." Analytical Chemistry 89, no. 24:13559-13566. PNNL-SA-129561. doi:10.1021/acs.analchem.7b03984
• Truex M.J., J.E. Szecsody, N. Qafoku, C.E. Strickland, J.J. Moran, B.D. Lee, and M. Snyder, et al. 2017. Contaminant Attenuation and Transport Characterization of 200-DV-1 Operable Unit Sediment Samples. PNNL-26208. Richland, WA: Pacific Northwest National Laboratory. Contaminant Attenuation and Transport Characterization of 200-DV-1 Operable Unit Sediment Samples">doi:10.2172/1368134.Contaminant Attenuation and Transport Characterization of 200-DV-1 Operable Unit Sediment Samples