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Fundamental and Computational Sciences Directorate

Staff information

William Nelson

Microbiome Science
Computational Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-18
Richland, WA 99352

PNNL Publications


  • Khan N.E., Y. Maezato, R.S. McClure, C.J. Brislawn, J.M. Mobberley, N.G. Isern, and W.B. Chrisler, et al. 2018. "Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture." Scientific Reports 8. PNNL-SA-129337. doi:10.1038/s41598-017-18630-1
  • Song H., W.C. Nelson, J. Lee, R.C. Taylor, C.S. Henry, A.S. Beliaev, and D. Ramkrishna, et al. 2018. "Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions." In Emerging Areas in Bioengineering, edited by HN Chang, et al. 793-801. Weinheim:Wiley-VCH Verlag GmbH & Co. PNNL-SA-115176. doi:10.1002/9783527803293.ch45


  • Bowers R.M., N. Kyrpides, R. Stepanauskas, M. Harmon-Smith, D. Doud, T. Reddy, and F. Schulz, et al. 2017. "Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea." Nature Biotechnology 35. PNNL-SA-125978. doi:10.1038/nbt.3893
  • Hou Z., W.C. Nelson, J.C. Stegen, C.J. Murray, E.V. Arntzen, A.R. Crump, and D.W. Kennedy, et al. 2017. "Geochemical and Microbial Community Attributes in Relation to Hyporheic Zone Geological Facies." Scientific Reports 7. PNNL-SA-121286. doi:10.1038/s41598-017-12275-w
  • Li M., Y. Gao, W. Qian, L. Shi, Y. Liu, W.C. Nelson, and C.D. Nicora, et al. 2017. "Targeted quantification of functional enzyme dynamics in environmental samples for microbially mediated biogeochemical processes." Environmental Microbiology Reports 9, no. 5:512-521. PNNL-SA-120732. doi:10.1111/1758-2229.12558
  • Lindemann S.R., J.M. Mobberley, J.K. Cole, L. Markillie, R.C. Taylor, E.L. Huang, and W.B. Chrisler, et al. 2017. "Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated ‘Omics Approach." Frontiers in Microbiology 8. PNNL-SA-129376. doi:10.3389/fmicb.2017.01020
  • Liu Y., C. Liu, W.C. Nelson, L. Shi, F. Xu, Y. Liu, and A. Yan, et al. 2017. "Effect of Water Chemistry and Hydrodynamics on Nitrogen Transformation and Microbial Community Functional Potential in Hyporheic Zone Sediment Columns." Environmental Science & Technology 51, no. 9:4877-4886. PNNL-SA-121316. doi:10.1021/acs.est.6b05018
  • Mobberley J.M., S.R. Lindemann, H.C. Bernstein, J.J. Moran, R.S. Renslow, J.T. Babauta, and D. Hu, et al. 2017. "Organismal and spatial partitioning of energy and macronutrient transformations within a hypersaline mat." FEMS Microbiology Ecology 93, no. 4:Article No. fix028. PNNL-SA-124562. doi:10.1093/femsec/fix028


  • Nelson W.C., Y. Maezato, Y. Wu, M.F. Romine, and S.R. Lindemann. 2016. "Identification and resolution of microdiversity through metagenomic sequencing of parallel consortia." Applied and Environmental Microbiology 82, no. 1:255-267. PNNL-SA-111129. doi:10.1128/AEM.02274-15
  • Stegen J.C., J.K. Fredrickson, M.J. Wilkins, A. Konopka, W.C. Nelson, E.V. Arntzen, and W.B. Chrisler, et al. 2016. "Groundwater-Surface Water Mixing Shifts Ecological Assembly Processes and Stimulates Organic Carbon Turnover." Nature Communications 7. PNNL-SA-111962. doi:10.1038/ncomms11237


  • Nelson W.C., and J.C. Stegen. 2015. "The reduced genomes of Parcubacteria (OD1) contain signatures of a symbiotic lifestyle." Frontiers in Microbiology 6. PNNL-SA-112374. doi:10.3389/fmicb.2015.00713
  • Walworth N.G., U. Pfreundt, W.C. Nelson, T. Mincer, J.F. Heidelberg, F. Fu, and J.B. Waterbury, et al. 2015. "Trichodesmium genome maintains abundant, widespread noncoding DNA in situ, despite oligotrophic lifestyle." Proceedings of the National Academy of Sciences of the United States of America 112, no. 4:4251-4256. PNNL-SA-108623. doi:10.1073/pnas.1422332112


  • Stolyar S., Z. Liu, V. Thiel, L.P. Tomsho, N. Pinel, W.C. Nelson, and S.R. Lindemann, et al. 2014. "Genome Sequence of the Thermophilic Cyanobacterium Thermosynechococcus sp. Strain NK55a." Genome Announcements 2, no. 1:Article No. e01060-13. PNNL-SA-100453. doi:10.1128/genomeA.01060-13

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