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Fundamental and Computational Sciences Directorate

Staff information

Lindsey Anderson

Computational Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-18
Richland, WA 99352

PNNL Publications

2025

  • Anderson L.N., C.T. Hoyt, J.D. Zucker, A.D. McNaughton, J.R. Teuton, K. Karis, and N.N. Arokium-Christian, et al. 2025. "Computational Tools and Data Integration to Accelerate Vaccine Development: Challenges, Opportunities, and Future Directions." Frontiers in Immunology 16, no. _:Art. No. 1502484. PNNL-SA-199005. doi:10.3389/fimmu.2025.1502484

2024

  • Eisfeld-Fenney A.J., L.N. Anderson, S. Fan, K.B. Walters, P.J. Halfmann, D. Westhoff-Smith, and L.B. Thackray, et al. 2024. "A compendium of multi-omics data illuminating host responses to lethal human virus infections." Scientific Data 11. PNNL-SA-189528. doi:10.1038/s41597-024-03124-3
  • Powell S.M., L.G. Jarlsberg, E. Zionce, L.N. Anderson, M.A. Gritsenko, P. Nahid, and J.M. Jacobs. 2024. "Longitudinal analysis of host protein serum signatures of treatment and recovery in pulmonary tuberculosis." PLoS One 19, no. 2:Art. No. e0294603. PNNL-SA-184858. doi:10.1371/journal.pone.0294603

2023

  • Gosline S., D. Kim, P. Pande, D.G. Thomas, L. Truong, P. Hoffman, and M. Barton, et al. 2023. "The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes." Scientific Data 10. PNNL-SA-177557. doi:10.1038/s41597-023-02021-5
  • Webber L.C., L.N. Anderson, I.L. Paraiso, T.O. Metz, R. Bradley, J.F. Stevens, and A.T. Wright. 2023. "Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli." RSC Advances 13, no. 42:29324-29331. PNNL-SA-190645. doi:10.1039/D3RA05296F

2022

  • Bhattacharjee A., O. Qafoku, J. Richardson, L.N. Anderson, K.C. Schwarz, L.M. Bramer, and G.X. Lomas, et al. 2022. "A Mineral-Doped Micromodel Platform Demonstrates Fungal Bridging of Carbon Hot Spots and Hyphal Transport of Mineral-Derived Nutrients." mSystems 7, no. 6:Art. No. e00913-22. PNNL-SA-167557. doi:10.1128/msystems.00913-22

2021

  • Danna V.G., H.D. Mitchell, L.N. Anderson, I.G. Godinez, S. Gosline, J.G. Teeguarden, and J.E. McDermott. 2021. "leapR: An R Package for MultiOmic Pathway Analysis." Journal of Proteome Research 20, no. 4:2116-2121. PNNL-SA-159351. doi:10.1021/acs.jproteome.0c00963

2020

  • Nelson W.C., L.N. Anderson, R. Wu, J.E. McDermott, S.L. Bell, A. Jumpponen, and S.J. Fansler, et al. 2020. "Terabase Metagenome Sequencing of Grassland Soil Microbiomes." Microbiology Resource Announcements 9, no. 32:Article No. e00718-20. PNNL-SA-153752. doi:10.1128/MRA.00718-20

2019

  • Dickinson M., L.N. Anderson, B.M. Webb-Robertson, J.R. Hansen, R.D. Smith, A.T. Wright, and K. Hybiske. 2019. "Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites." PLoS Pathogens 15, no. 4:Article Number e1007698. PNNL-SA-132851. doi:10.1371/journal.ppat.1007698
  • Merkley E.D., K.E. Burnum-Johnson, L.N. Anderson, S.C. Jenson, and K.L. Wahl. 2019. "Uniformly 15N-Labeled Recombinant Ricin A-chain as an Internal Retention Time Standard for Increased Confidence in Forensic Identification of Ricin by Untargeted Nanoflow Liquid Chromatography-Tandem Mass Spectrometry." Analytical Chemistry 91, no. 21:13372-13376. PNNL-SA-145704. doi:10.1021/acs.analchem.9b03389

2018

  • Ortega C., A. Frando, B.M. Webb-Robertson, L.N. Anderson, N. Fleck, E.L. Flannery, and M. Fishbaugher, et al. 2018. "A global survey of ATPase activity in Plasmodium falciparum asexual blood stages and gametocytes." Molecular & Cellular Proteomics 17, no. 1:111-120. PNNL-SA-121236. doi:10.1074/mcp.RA117.000088

2017

  • Romine M.F., D.A. Rodionov, Y. Maezato, L.N. Anderson, P. Nandhikonda, I.A. Rodionova, and A. Carre, et al. 2017. "Elucidation of new roles for vitamin B12 in regulation of folate, ubiquinone, and methionine metabolism." Proceedings of the National Academy of Sciences (PNAS) 114, no. 7:E1205-E1214. PNNL-SA-119181. doi:10.1073/pnas.1612360114
  • Rosnow J.J., L.N. Anderson, R.N. Nair, E.S. Baker, and A.T. Wright. 2017. "Profiling microbial lignocellulose degradation and utilization by emergent omics technologies." Critical Reviews in Biotechnology 37, no. 5:626-640. PNNL-SA-116817. doi:10.1080/07388551.2016.1209158

2016

  • Anderson L.N., P.K. Koech, A.E. Plymale, E.V. Landorf, A. Konopka, F. Collart, and M.S. Lipton, et al. 2016. "Live Cell Discovery of Microbial Vitamin Transport and Enzyme-Cofactor Interactions." ACS Chemical Biology 11, no. 2:345-354. PNNL-SA-108145. doi:10.1021/acschembio.5b00918
  • Ortega C., L.N. Anderson, A. Frando, N.C. Sadler, R.W. Brown, R.D. Smith, and A.T. Wright, et al. 2016. "Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence." Cell Chemical Biology 23, no. 2:290-298. PNNL-SA-112430. doi:10.1016/j.chembiol.2016.01.003
  • Sadler N.C., H.C. Bernstein, M.R. Melnicki, M.A. Charania, E.A. Hill, L.N. Anderson, and M.E. Monroe, et al. 2016. "Dinitrogenase Driven Photobiological Hydrogen Production Combats Oxidative Stress in Cyanothece sp. ATCC 51142." Applied Environmental Microbiology 82, no. 24:7227-7235. PNNL-SA-113160. doi:10.1128/AEM.02098-16
  • Sadler N.C., P. Nandhikonda, B.M. Webb-Robertson, C. Ansong, L.N. Anderson, J.N. Smith, and R.A. Corley, et al. 2016. "Hepatic cytochrome P450 activity, abundance, and expression throughout human development." Drug Metabolism and Disposition 44, no. 7:984-91. PNNL-SA-112422. doi:10.1124/dmd.115.068593

2015

  • Wright A.T., T. Magnaldo, R.L. Sontag, L.N. Anderson, N.C. Sadler, P.D. Piehowski, and Y. Gache, et al. 2015. "Deficient Expression of Aldehyde Dehydrogenase 1A1 Is Consistent with Increased Sensitivity of Gorlin Syndrome Patients to Radiation Carcinogenesis." Molecular Carcinogenesis 54, no. 6:473-484. PNNL-SA-95210. doi:10.1002/mc.22115

2014

  • Ortega C., R. Liao, L.N. Anderson, T. Rustad, A.R. Ollodart, A.T. Wright, and D.R. Sherman, et al. 2014. "Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch." PLoS Biology 12, no. 1:Article No. e1001746. PNNL-SA-94282. doi:10.1371/journal.pbio.1001746
  • Wiedner S.D., L.N. Anderson, N.C. Sadler, W.B. Chrisler, V.K. Kodali, R.D. Smith, and A.T. Wright. 2014. "Organelle-Specific Activity-Based Protein Profiling in Living Cells." Angewandte Chemie International Edition 53, no. 11:2919-2922. PNNL-SA-98713. doi:10.1002/anie.201309135

2013

  • Anderson L.N., D.E. Culley, B.A. Hofstad, L.M. Chauvigne-Hines, E.M. Zink, S.O. Purvine, and R.D. Smith, et al. 2013. "Activity-based protein profiling of secreted cellulolytic enzyme activity dynamics in Trichoderma reesei QM6a, NG14, and RUT-C30." Molecular Biosystems 9, no. 12:2992-3000. PNNL-SA-97265. doi:10.1039/c3mb70333a

2012

  • Chauvigne-Hines L.M., L.N. Anderson, H.M. Weaver, J.N. Brown, P.K. Koech, C.D. Nicora, and B.A. Hofstad, et al. 2012. "Suite of Activity-Based Probes for Cellulose-Degrading Enzymes." Journal of the American Chemical Society 134, no. 50:20521-20532. PNNL-SA-91066. doi:10.1021/ja309790w
  • Wiedner S.D., K.E. Burnum, L.M. Pederson, L.N. Anderson, S. Fortuin, L.M. Chauvigne-Hines, and A.K. Shukla, et al. 2012. "Multiplexed Activity-based Protein Profiling of the Human Pathogen Aspergillus fumigatus Reveals Large Functional Changes upon Exposure to Human Serum." Journal of Biological Chemistry 287, no. 40:33447-33459. PNNL-SA-87258. doi:10.1074/jbc.M112.394106

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