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Fundamental and Computational Sciences Directorate

Staff information

John Cort

Instrument Dev & Deployment
Pacific Northwest National Laboratory
PO Box 999
MSIN: K8-98
Richland, WA 99352

Research Interests

  • biomolecular NMR spectroscopy
  • structure-based functional genomics

Education and Credentials

  • B.A. Williams College, 1991
  • Ph.D. University of Washington, 1997

PNNL Publications


  • Meng Q., S. Moinuddin, R.M. Celoy, C. Smith, R.P. Young, M.A. Costa, and R.A. Freeman, et al. 2024. "Dirigent isoflavene-forming PsPTS2: 3D Structure, stereochemical and kinetic characterization comparison with pterocarpan-forming PsPTS1 homolog in pea." Journal of Biological Chemistry 300, no. 3:Art. No. 105647. PNNL-SA-188847. doi:10.1016/j.jbc.2024.105647
  • Powers R., E.R. Andersson, A.L. Bayless, R.B. Brua, M.C. Chang, L.L. Cheng, and C.S. Clendinen, et al. 2024. "Best Practices in NMR Metabolomics: Current State." Trends in Analytical Chemistry 171. PNNL-SA-193426. doi:10.1016/j.trac.2023.117478


  • Pin M., E. Poynton, T. Jordan, J. Kim, B. Ledingham, J.A. van Santen, and V. Yang, et al. 2023. "A Data Deposition Platform for Sharing Nuclear Magnetic Resonance Data." Journal of Natural Products 86, no. 11:2554-2561. PNNL-SA-191996. doi:10.1021/acs.jnatprod.3c00795


  • Bays J.T., R. Gieleciak, M.B. Viola, R.P. Lewis, J.R. Cort, K.B. Campbell, and G.W. Coffey, et al. 2022. "Detailed Compositional Comparison of Hydrogenated Vegetable Oil with Several Diesel Fuels and their Effect on Engine Emissions." SAE International Journal of Fuels and Lubricants 16, no. 3. PNNL-SA-166133. doi:10.4271/04-16-03-0015
  • Cruz-Morales P., K. Yin, A. Landera, J.R. Cort, R.P. Young, J.E. Kyle, and R. Bertrand, et al. 2022. "Biosynthesis of polycyclopropanated high energy biofuels." Joule 6, no. 7:1590-1605. PNNL-SA-170223. doi:10.1016/j.joule.2022.05.011
  • Wu R., C. Smith, G.W. Buchko, I.K. Blaby, A. Paez-Espino, N.C. Kyrpides, and Y. Yoshikuni, et al. 2022. "Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase." Nature Communications 13, no. 1:Art. No. 5485. PNNL-SA-170607. doi:10.1038/s41467-022-32993-8
  • Xu Z., B. Peng, R. Kitata, C.D. Nicora, K.K. Weitz, Y. Pu, and T. Shi, et al. 2022. "Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis." Biotechnology for Biofuels and Bioproducts 15, no. 1:Art. No. 117. PNNL-SA-172168. doi:10.1186/s13068-022-02214-x
  • Yang Z., Z. Xu, M. Feng, J.R. Cort, R. Gieleciak, J.S. Heyne, and B. Yang. 2022. "Lignin-based Jet Fuel and its Blending effect with Conventional Jet Fuel." Fuel 321. PNNL-SA-168716. doi:10.1016/j.fuel.2022.124040


  • Li X., Z. Xu, J.R. Cort, W. Qian, and B. Yang. 2021. "Lipid production from non-sugar compounds in pretreated lignocellulose hydrolysates by Rhodococcus jostii RHA1." Biomass & Bioenergy 145. PNNL-SA-153203. doi:10.1016/j.biombioe.2021.105970
  • Ma R., U. Sanyal, M.V. Olarte, H.M. Job, M.S. Swita, S.B. Jones, and P.A. Meyer, et al. 2021. "Role of peracetic acid on the disruption of lignin packing structure and its consequence on lignin depolymerisation." Green Chemistry 23, no. 21:8468-8479. PNNL-SA-159270. doi:10.1039/D1GC02300D
  • Xu Z., C. Pan, X. Li, N. Hao, T. Zhang, M.J. Gaffrey, and Y. Pu, et al. 2021. "Enhancement of Polyhydroxyalkanoate Production by Co-feeding Lignin Derivatives with Glycerol in Pseudomonas putida KT2440." Biotechnology for Biofuels 14, no. 1:Article No. 11. PNNL-SA-157585. doi:10.1186/s13068-020-01861-2


  • Garcellano R.C., J.R. Cort, S. Moinuddin, S.G. Fransblau, R. Ma, and A.M. Aguinaldo. 2020. "An iboga alkaloid chemotaxonomic marker from endemic Tabernaemontana ternifolia with antitubercular activity." Natural Product Research 34, no. 8:1175-1179. PNNL-SA-139640. doi:10.1080/14786419.2018.1550759
  • Heredia-Langner A., J.R. Cort, K. Grubel, M.J. O'Hagan, K.H. Jarman, J.C. Linehan, and K.O. Albrecht, et al. 2020. "Methodology for the development of empirical models relating 13C NMR spectral features to fuel properties." Energy and Fuels 34, no. 10:12556-12572. PNNL-SA-152125. doi:10.1021/acs.energyfuels.0c00883
  • Meng Q., S. Moinuddin, S. Kim, D.L. Bedgar, M.A. Costa, D.G. Thomas, and R.P. Young, et al. 2020. "Pterocarpan synthase (PTS) structures suggest a common quinone methide-stabilizing function in dirigent proteins and proteins with dirigent-like domains." Journal of Biological Chemistry 295, no. 33:11584-11601. PNNL-SA-150677. doi:10.1074/jbc.RA120.012444
  • Tolkatchev D., G.E. Smith, L.E. Schultz, M. Colpan, G.L. Helms, J.R. Cort, and C.C. Gregorio, et al. 2020. "Leiomodin creates a leaky cap at the pointed end of actin-thin filaments." PLoS Biology 18, no. 9:e3000848. PNNL-SA-153254. doi:10.1371/journal.pbio.3000848
  • Zhang L., Z. Xu, J.R. Cort, T. Vuorinen, and B. Yang. 2020. "Flowthrough Pretreatment of Softwood under Water-only and Alkali Conditions." Energy and Fuels 34, no. 12:16310-16319. PNNL-SA-157576. doi:10.1021/acs.energyfuels.0c03374


  • Cort J.R., I.V. Novikova, and J.E. Evans. 2019. MicroED for rapid and comprehensive characterization of the unknown small molecule composition of crude plant and soil extracts. PNNL-29546. Richland, WA: Pacific Northwest National Laboratory. MicroED for rapid and comprehensive characterization of the unknown small molecule composition of crude plant and soil extracts
  • Garcellano R.C., S. Moinuddin, R.P. Young, M.E. Bowden, M. Zhou, R.S. Renslow, and Y. Yesiltepe, et al. 2019. "Isolation of Tryptanthrin and Reassessment of Evidence for its Isobaric Isostere Wrightiadione in Plants of the Wrightia Genus." Journal of Natural Products 82, no. 3:440-448. PNNL-SA-135279. doi:10.1021/acs.jnatprod.8b00567
  • McDermott J.E., J.R. Cort, E.S. Nakayasu, J.N. Pruneda, C.C. Overall, and J.N. Adkins. 2019. "Prediction of Bacterial E3 Ubiquitin Ligase Effectors using Reduced Amino Acid Peptide Fingerprinting." PeerJ 7. PNNL-SA-138492. doi:10.7717/peerj.7055
  • Moinuddin S., J.R. Cort, C.A. Smith, C. Hano, L.B. Davin, and N.G. Lewis. 2019. "Linum Lignan and Associated Biochemical Pathways in Human Health and Plant Defense." In Genetics and Genomics of Linum, edited by CA Cullis. 167-193. Cham:Springer Nature. PNNL-SA-139543. doi:10.1007/978-3-030-23964-0_11


  • Brinson R.G., J.P. Marino, F. Delaglio, L.W. Arbogast, R.M. Evans, A. Kearsley, and G. Gingras, et al. 2018. "Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics." mAbs 11, no. 1:94-105. PNNL-SA-131540. doi:10.1080/19420862.2018.1544454
  • Brittain A.D., N.J. Chrisandina, R.E. Cooper, M. Buchanan, J.R. Cort, M.V. Olarte, and C. Sievers. 2018. "Quenching of Reactive Intermediates During Mechanochemical Depolymerization of Lignin." Catalysis Today 302. PNNL-SA-120623. doi:10.1016/j.cattod.2017.04.066
  • Corbin C., S. Drouet, L. Markulin, D. Auguin, D. Auguin, E. Laine, and L.B. Davin, et al. 2018. "A genome-wide analysis of the flax (Linum usitatissimum L.) dirigent protein family: from gene identification and evolution to differential regulation." Plant Molecular Biology 97, no. 1-2:73-101. PNNL-SA-131411. doi:10.1007/s11103-018-0725-x
  • Dutta T., G. Papa, E. Wang, J. Sun, N.G. Isern, J.R. Cort, and B.A. Simmons, et al. 2018. "Characterization of lignin streams during bionic liquid-based pretreatment from grass, hardwood and softwood." ACS Sustainable Chemistry & Engineering 6, no. 3:3079-3090. PNNL-SA-131395. doi:10.1021/acssuschemeng.7b02991
  • Oliveira F.C., K. Srinivas, G.L. Helms, N.G. Isern, J.R. Cort, A.R. Goncalves, and B.K. Ahring. 2018. "Characterization of coffee (Coffea arabica) husk lignin and degradation products obtained after oxygen and alkali addition." Bioresource Technology 257. PNNL-SA-131064. doi:10.1016/j.biortech.2018.01.041
  • Sun J., D. Liu, R.P. Young, A.G. Cruz, N.G. Isern, T. Schuerg, and J.R. Cort, et al. 2018. "Solubilization and Upgrading of High Polyethylene Terephthalate Loadings in a Low-Costing Bifunctional Ionic Liquid." ChemSusChem 11, no. 4:781-792. PNNL-SA-128561. doi:10.1002/cssc.201701798


  • Dutta T., N.G. Isern, J. Sun, E. Wang, S. Hull, J.R. Cort, and B.A. Simmons, et al. 2017. "Survey of Lignin-Structure Changes and Depolymerization during Ionic Liquid Pretreatment." ACS Sustainable Chemistry & Engineering 5, no. 11:10116-10127. PNNL-SA-125980. doi:10.1021/acssuschemeng.7b02123
  • Hosseinzadeh P., G. Bhardwaj, V.K. Mulligan, M.D. Shortridge, T.W. Craven, F. Pardo-Avila, and S.A. Rettie, et al. 2017. "Comprehensive computational design of ordered peptide macrocycles." Science 358, no. 6369:1461-1466. PNNL-SA-128820. doi:10.1126/science.aap7577
  • Kim K., T. Dutta, E.D. Walter, N.G. Isern, J.R. Cort, B.A. Simmons, and S. Singh. 2017. "Chemoselective Methylation of Phenolic Hydroxyl Group Prevents Quinone Methide Formation and Repolymerization during Lignin Depolymerization." ACS Sustainable Chemistry & Engineering 5, no. 5:3913-3919. PNNL-SA-122183. doi:10.1021/acssuschemeng.6b03102
  • Nakayasu E.S., M.C. Burnet, H.E. Walukiewicz, C.S. Wilkins, A.K. Shukla, S.M. Brooks, and M.J. Plutz, et al. 2017. "Ancient regulatory role of lysine acetylation in central metabolism." mBio 8, no. 6:Article No. e01894-17. PNNL-SA-124565. doi:10.1128/mBio.01894-17
  • Tan K., B. Kaiser, R. Wu, M. Cuff, Y. Fan, L. Bigelow, and R. Jedrzejczak, et al. 2017. "Insights into PG-binding, conformational change, and dimerization of the OmpAC-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi." Protein Science 26, no. 9:1738-1748. PNNL-SA-126827. doi:10.1002/pro.3209
  • Turner M.W., J.R. Cort, and O.M. Mcdougal. 2017. "a-Conotoxin Decontamination Protocol Evaluation: What Works and What Doesn’t." Toxins 9, no. 9:281. PNNL-SA-129342. doi:10.3390/toxins9090281


  • Colpan M., D. Tolkatchev, S.L. Grover, G.L. Helms, J.R. Cort, N. Moroz, and A.S. Kostyukova. 2016. "Localization of the binding interface between leiomodin-2 and a-tropomyosin." Biochimica et Biophysica Acta--Proteins and Proteomics 1864, no. 5:523-530. PNWD-SA-10530. doi:10.1016/j.bbapap.2016.02.009
  • Everett J.K., R. Tejero, S.B. Murthy, T. Acton, J.M. Aramini, M. Baran, and J. Benach, et al. 2016. "A Community Resource of Experimental Data for NMR / X-ray Crystal Structure Pairs." Protein Science 25, no. 1:30-45. PNWD-SA-10501. doi:10.1002/pro.2774
  • Sun J., T. Dutta, R. Parthasarathi, K. Kim, N. Tolic, R.K. Chu, and N.G. Isern, et al. 2016. "Rapid room temperature solubilization and depolymerization of polymeric lignin at high loadings." Green Chemistry 18, no. 22:6012-6020. PNNL-SA-120307. doi:10.1039/C6GC02258H
  • Wang H., L. Zhang, T. Deng, H. Ruan, X. Hou, J.R. Cort, and B. Yang. 2016. "ZnCl2 Induced Catalytic Conversion of Softwood Lignin to Aromatics and Hydrocarbons." Green Chemistry 18, no. 9:2802-2810. PNNL-SA-115052. doi:10.1039/C5GC02967H
  • Zhang L., Y. Pu, J.R. Cort, A.J. Ragauskas, and B. Yang. 2016. "Revealing the Molecular Structural Transformation of Hardwood and Softwood in Dilute Acid Flowthrough Pretreatment." ACS Sustainable Chemistry & Engineering 4, no. 2:6618-6628. PNNL-SA-120912. doi:10.1021/acssuschemeng.6b01491


  • Kim K., C.A. Smith, M.D. Daily, J.R. Cort, L.B. Davin, and N.G. Lewis. 2015. "Trimeric Structure of (+)-Pinoresinol-forming Dirigent Protein at 1.95 Resolution with Three Isolated Active Sites." Journal of Biological Chemistry 290, no. 3:1308-1318. PNWD-SA-10390. doi:10.1074/jbc.M114.611780
  • Sontag R.L., C. Mihai, G. Orr, A. Savchenko, T. Skarina, H. Cui, and J.R. Cort, et al. 2015. "Electroporation of Functional Bacterial Effectors into Mammalian Cells." Journal of Visualized Experiments 95. PNNL-SA-102481. doi:10.3791/52296
  • Wang H., H. Ruan, H. Pei, H. Wang, X. Chen, M.p. Tucker, and J.R. Cort, et al. 2015. "Biomass-derived Lignin to Jet Fuel Range Hydrocarbons via Aqueous Phase Hydrodeoxygenation." Green Chemistry 17, no. 12:5131-5135. PNNL-SA-112582. doi:10.1039/C5GC01534K
  • Zhang L., L. Yan, Z. Wang, D.D. Laskar, M.S. Swita, J.R. Cort, and B. Yang. 2015. "Characterization of Lignin Derived from Water-only and Dilute Acid Flowthrough Pretreatment of Poplar Wood at Elevated Temperatures." Biotechnology for Biofuels 8. PNNL-SA-113147. doi:10.1186/s13068-015-0377-x


  • Eletsky A., K. Michalska, S. Houliston, Q. Zhang, M.D. Daily, X. Xu, and H. Cui, et al. 2014. "Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO." PLoS One 9, no. 7:Article No. e101787. PNNL-SA-101092. doi:10.1371/journal.pone.0101787
  • Sudasinghe N., J.R. Cort, R.T. Hallen, M.V. Olarte, A.J. Schmidt, and T. Schaub. 2014. "Hydrothermal Liquefaction Oil and Hydrotreated Product from Pine Feedstock Characterized by Heteronuclear Two-Dimensional NMR Spectroscopy and FT-ICR Mass Spectrometry." Fuel 137. PNNL-SA-102800. doi:10.1016/j.fuel.2014.07.069


  • Ansong C., S. Wu, D. Meng, X. Liu, H.M. Brewer, B. Kaiser, and E.S. Nakayasu, et al. 2013. "Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typimurium in response to infection-like conditions." Proceedings of the National Academy of Sciences of the United States of America 110, no. 25:10153-10158. PNNL-SA-92306. doi:10.1073/pnas.1221210110
  • Fu N., D. Su, J.R. Cort, B. Chen, Y. Xiong, W. Qian, and A. Konopka, et al. 2013. "Synthesis and Application of an Environmentally Insensitive Cy3-Based Arsenical Fluorescent Probe to Identify Adaptive Microbial Responses Involving Proximal Dithiol Oxidation." Journal of the American Chemical Society 135, no. 9:3567-3575. PNNL-SA-92302. doi:10.1021/ja3117284
  • Isern N.G., J. Xue, J.V. Rao, J.R. Cort, and B.K. Ahring. 2013. "Novel monosaccharide fermentation products in Caldicellulosiruptor saccharolyticus identified using NMR spectroscopy." Biotechnology for Biofuels 6, no. 4:Article No. 47. PNNL-SA-92676. doi:10.1186/1754-6834-6-47
  • Merkley E.D., E.S. Baker, K.L. Crowell, D.J. Orton, T. Taverner, C. Ansong, and Y.M. Ibrahim, et al. 2013. "Mixed-Isotope Labeling with LC-IMS-MS for Characterization of Protein-Protein Interactions by Chemical Cross-Linking." Journal of the American Society for Mass Spectrometry 24, no. 3:444-449. PNNL-SA-88464. doi:10.1007/s13361-012-0565-x
  • Merkley E.D., J.R. Cort, and J.N. Adkins. 2013. "Cross-Linking and Mass Spectrometry Methodologies to Facilitate Structural Biology: Finding a Path through the Maze." Journal of Structural and Functional Genomics 14, no. 3:77-90. PNNL-SA-94079. doi:10.1007/s10969-013-9160-z
  • Metaxas A.E., and J.R. Cort. 2013. "Counterion influence on chemical shifts in strychnine salts." Magnetic Resonance in Chemistry 51, no. 5:292-298. PNNL-SA-90772. doi:10.1002/mrc.3945
  • Michalska K., R.N. Brown, H. Li, R. Jedrzejczak, G. Niemann, F. Heffron, and J.R. Cort, et al. 2013. "New sub-family of lysozyme-like proteins shows no catalytic activity: crystallographic and biochemical study of STM3605 protein from Salmonella Typhimurium." Journal of Structural and Functional Genomics 14, no. 1:1-10. PNNL-SA-93811. doi:10.1007/s10969-013-9151-0
  • Venceslau S.S., J.R. Cort, E.S. Baker, R.K. Chu, E.W. Robinson, C. Dahl, and L.M. Saraiva, et al. 2013. "Redox states of Desulfovibrio vulgaris DsrC, a key protein in dissimilatory sulfite reduction." Biochemical and Biophysical Research Communications 441, no. 4:731-736. PNNL-SA-98016. doi:10.1016/j.bbrc.2013.10.116


  • Cort J.R., P.J. Alperin, and H.M. Cho. 2012. "Measurement and analysis of diastereomer ratios for forensic characterization of brodifacoum." Forensic Science International 214, no. 1-3:178-181. PNNL-SA-68262. doi:10.1016/j.forsciint.2011.08.003
  • Snyder D.A., J.M. Aramini, B. Yu, Y. Huang, R. Xiao, J.R. Cort, and R. Shastry, et al. 2012. "Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus." Proteins. Structure, Function, and Bioinformatics 80, no. 7:1901-1906. PNWD-SA-9744.
  • Yang Y., T.A. Ramelot, J.R. Cort, M. Garcia, A. Yee, C.H. Arrowsmith, and M.A. Kennedy. 2012. "Solution NMR Structure of Hypothetical Protein CV_2116 Encoded by a Viral Prophage Element in Chromobacterium violaceum." International Journal of Molecular Sciences 13, no. 6:7354-7364. PNWD-SA-9740. doi:10.3390/ijms13067354


  • Barb A.W., J.R. Cort, J. Seetharaman, S. Lew, H. Lee, T. Acton, and R. Xiao, et al. 2011. "Structures of Domains I and IV from YbbR are representative of a widely distributed protein family." Protein Science 20, no. 2:396-405. PNWD-SA-9037. doi:10.1002/pro.571
  • Cort J.R., M. Swenson, and T.S. Magnuson. 2011. "1H, 13C, and 15N backbone, side-chain, and heme chemical shift assignments for oxidized and reduced forms of the monoheme c-type cytochrome ApcA isolated from the acidophilic metal-reducing bacterium Acidiphilium cryptum." Biomolecular NMR Assignments 5, no. 1:89-92. PNNL-SA-74669. doi:10.1007/s12104-010-9274-1
  • Yin C., J.M. Aramini, L. Ma, J.R. Cort, G. Swapna, R.M. Krug, and G. Montelione. 2011. "Backbone and Ile-d1, Leu, Val Methyl 1H, 13C and 15N NMR chemical shift assignments for human interferon-stimulated gene 15 protein." Biomolecular NMR Assignments 5, no. 2:215-219. PNNL-SA-82785. doi:10.1007/s12104-011-9303-8


  • Aramini J.M., P. Rossi, J.R. Cort, L. Ma, R. Xiao, T. Acton, and G. Montelione. 2010. "Solution NMR structure of the plasmid-encoded fimbriae regulatory protein PefI from Salmonella enterica serovar Typhimurium." Proteins. Structure, Function, and Bioinformatics 79, no. 1:335-339. PNWD-SA-9032. doi:10.1002/prot.22869
  • Grimm F., F. Grimm, J.R. Cort, and C. Dahl. 2010. "DsrR, a Novel IscA-like Protein Lacking Iron- and Fe-S-Binding Functions, Involved in the Regulation of Sulfur Oxidation in Allochromatium Vinosum." Journal of Bacteriology 192, no. 6:1652-1661. PNWD-SA-8725. doi:10.1128/JB.01269-09
  • Tang Z., H. Wu, J.R. Cort, G.W. Buchko, Y. Zhang, Y. Shao, and I.A. Aksay, et al. 2010. "Constraint of DNA on Functionalized Graphene Improves Its Biostability and Specificity." Small 6, no. 11:1205-1209. PNNL-SA-67870. doi:10.1002/smll.201000024
  • Yang Y., T.A. Ramelot, J.R. Cort, D. Wang, C. Ciccosanti, K. Hamilton, and R. Nair, et al. 2010. "Solution NMR Structure of Photosystem II Reaction Center Protein Psb28 from Synechocystin sp. Strain PCC 6803." Proteins. Structure, Function, and Bioinformatics 79, no. 1:340-344. PNWD-SA-8966. doi:10.1002/prot.22876
  • Yang Y., T.A. Ramelot, R.M. McCarrick, S. Ni, E.A. Feldmann, J.R. Cort, and H. Wang, et al. 2010. "Combining NMR, PRE, and EPR Methods For Homodimer Protein Structure Determination." Journal of the American Chemical Society 132, no. 34:11910-11913. PNWD-SA-9000. doi:10.1021/ja105080h


  • Bertonati C., M. Punta, M. Fischer, G. Yachdav, F. Forouhar, W. Zhou, and A.P. Kuzin, et al. 2009. "Structural genomics reveals EVE as a new ASCH/PUA-related domain." Proteins. Structure, Function, and Bioinformatics 75, no. 3:760-773. PNWD-SA-8091.
  • Cort J.R., and H.M. Cho. 2009. "1H and 13C NMR Chemical Shift Assignments and Conformational Analysis for the Two Diastereomers of the Vitamin K Epoxide Reductase Inhibitor Brodifacoum." Magnetic Resonance in Chemistry 47, no. 10:897-901. PNNL-SA-65819. doi:10.1002/mrc.2475
  • Mercier K.A., J.R. Cort, M.A. Kennedy, E.E. Lockert, E.E. Lockert, S. Ni, and M.D. Shortridge, et al. 2009. "Structure and Function of Pseudomonas Aeruginosa Protein PA1324 (21-170)." Protein Science 18, no. 3:606-618. PNWD-SA-8406.


  • Buchko G.W., J.G. Bekhazi, J.R. Cort, N.B. Valentine, M.L. Snead, and W.J. Shaw. 2008. "1H, 13C, and 15N resonance assignments of murine amelogenin, an enamel biomineralization protein." Biomolecular NMR Assignments 2, no. 1:89-91. PNNL-SA-59235.
  • Cort J.R., T.A. Ramelot, D. Murray, T. Acton, L. Ma, R. Xiao, and G. Montelione, et al. 2008. "Structure of an Acetyl-CoA Binding Protein from Staphylococcus aureus Representing a Novel Subfamily of GCN5-related N-Acetyltransferase-like Proteins." Journal of Structural and Functional Genomics 9, no. 1-4:7-20. PNWD-SA-7786. doi:10.1007/s10969-008-9041-z
  • Cort J.R., U. Selan, A. Schulte, F. Grimm, F. Grimm, M.A. Kennedy, and C. Dahl. 2008. "Allochromatium vinosum DsrC: Solution-State NMR Structure, Redox Properties and Interaction with DsrEFH, a Protein Essential for Purple Sulfur Bacterial Sulfur Oxidation." Journal of Molecular Biology 382. PNWD-SA-8188. doi:10.1016/j.jmb.2008.07.022
  • Wu B., A. Yee, Y. Huang, T.A. Ramelot, J.R. Cort, A. Semesi, and J. Jung, et al. 2008. "The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain." Protein Science 17, no. 3:583-588. PNWD-SA-7954.


  • Aramini J.M., Y. Huang, G. Swapna, J.R. Cort, P.K. Rajan, R. Xiao, and R. Shastry, et al. 2007. "The solution NMR structure of Escherichia coli ytfP expands the structural coverage of the UPF0131 protein domain family." Proteins. Structure, Function, and Bioinformatics 68. PNWD-SA-7702. doi:10.1002/prot.21450
  • Ramelot T.A., A. Yee, J.R. Cort, A. Semesi, C.H. Arrowsmith, and M.A. Kennedy. 2007. "NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein." Proteins. Structure, Function, and Bioinformatics 66, no. 2:266-271. PNNL-SA-50033. doi:10.1002/prot.21199


  • Aramini J.M., G. Swapna, Y. Huang, P.K. Rajan, R. Xiao, R. Shastry, and T. Acton, et al. 2005. "1H, 13C, and 15N resonance assignments for Escherichia coli ytfP, a member of the broadly conserved UPF0131 protein domain family." Journal of Biomolecular NMR 33, no. 3:197. PNWD-SA-7240.
  • Powers R., N. Mirkovic, S. Goldsmith-Fischman, T. Acton, Y. Chiang, Y. Huang, and L. Ma, et al. 2005. "Solution Structure of Archaeoglobus fulgidis Peptidyl-tRNA Hydrolase(Pth2) Provides Evidence for an Extensive Conserved Family of Pth2 Enzymes in Archaea, Bacteria and Eukaryotes." Protein Science 14, no. 11:2849-2861. PNWD-SA-7097.
  • Savchenko A., N. Krogan, J.R. Cort, E. Evdokimova, J.M. Lew, A. Yee, and L. Sanchez-Pulido, et al. 2005. "The Shwachman-Bodian-Diamond Syndrome Protein Family Is Involved in RNA Metabolism." Journal of Biological Chemistry 280, no. 19:19213-19220. PNNL-SA-45303. doi:10.1074/jbc.M414421200


  • Powers R., T. Acton, Y. Chiang, P.K. Rajan, J.R. Cort, M.A. Kennedy, and J. Liu, et al. 2004. "Letter to the Editor: H-1, C-13 and N-15 Assignments for the Archaeglobus fulgidis Protein AF2095." Journal of Biomolecular NMR 30, no. 1:107-108. PNWD-SA-6538.
  • Ramelot T.A., J.R. Cort, S. Goldsmith-Fischman, G.J. Kornhaber, R. Xiao, R. Shastry, and T. Acton, et al. 2004. "Solution NMR Structure of the Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site." Journal of Molecular Biology 344, no. 2:567-583. PNNL-SA-41226.


  • Aramini J.M., Y. Huang, J.R. Cort, S. Goldsmith-Fischman, R. Xiao, L. Shih, and C.K. Ho, et al. 2003. "Solution NMR Structure of the 30S Ribosomal Protein S28E From Pyrococcus Horikoshii." Protein Science 12, no. 12:2823-2830. PNWD-SA-6107.
  • Pineda-Lucena A., J. Liao, J.R. Cort, A. Yee, M.A. Kennedy, A.M. Edwards, and C.H. Arrowsmith. 2003. "A novel member of the split betaalphabeta fold: Solution structure of the hypothetical protein YML108W from Saccharomyces cerevisiae." Protein Science 12, no. 5:1136-1140. PNWD-SA-5917.
  • Ramelot T.A., J.R. Cort, A. Yee, A. Semsesi, A.M. Edwards, C.H. Arrowsmith, and M.A. Kennedy. 2003. "Solution Structure of the Yeast Ubiquitin-Like Modifier Protein Hub1." Journal of Structural and Functional Genomics 4, no. 1:25-30. PNWD-SA-5795.
  • Ramelot T.A., S. Ni, S. Goldsmith-Fischman, J.R. Cort, B. Honig, and M.A. Kennedy. 2003. "Solution Structure of Vibrio Cholerae Protein VC0424: A Variation of the Ferredoxin-like Fold." Protein Science 12, no. 7:1556-1561. PNWD-SA-5995.
  • Wu B., A. Yee, A. Pineda-Lucena, A. Semesi, T.A. Ramelot, J.R. Cort, and J. Jung, et al. 2003. "Solution Structure of Ribosomal Protein S28E From Methanobacterium Thermoautotrophicum." Protein Science 12, no. 12:2831-2837. PNWD-SA-6105.
  • Zheng D., J.R. Cort, Y. Chiang, T. Acton, M.A. Kennedy, and G. Montelione. 2003. "Letter to the Editor: 1H, 13C and 15N Resonance Assignments for Methionine Sulfoxide Reductase B from Bacillus Subtilis." Journal of Biomolecular NMR 27, no. 2:183-184. PNWD-SA-5912.


  • Cort J.R., Y. Chiang, D. Zheng, M.A. Kennedy, and G. Montelione. 2002. "NMR Structure of Conserved Eukaryotic Protein ZK652.3 from C. elegans: a Ubiquitin-like Fold." Proteins. Structure, Function, and Genetics 48, no. 4:733-736. PNWD-SA-5666.
  • Pineda-Lucena A., G. Yi, X. Chang, J.R. Cort, M.A. Kennedy, A.M. Edwards, and C.H. Arrowsmith. 2002. "Letter to the Editor: Solution Structure of the Hypothetical Protein MTH0637 from Methanobacterium Thermoautotrophicum." Journal of Biomolecular NMR 22, no. 3:291-294. PNWD-SA-5705.
  • Pineda-Lucena A., J. Liao, B. Wu, A. Yee, J.R. Cort, M.A. Kennedy, and A.M. Edwards, et al. 2002. "NMR Structure of the hypothetical protein encoded by the YjbJ gene from Escherichia coli." Proteins. Structure, Function, and Genetics 47, no. 4:572-574. PNWD-SA-5619.
  • Ramelot T.A., J.R. Cort, A. Yee, A. Semesi, A.M. Edwards, C.H. Arrowsmith, and M.A. Kennedy. 2002. "NMR Structure of the Escherichia Coli Protein YacG; A Novel Sequence Motif in the Zinc-Finger Family of Proteins." Proteins. Structure, Function, and Genetics 49, no. 2:289-293. PNWD-SA-5717.
  • Ramelot T.A., J.R. Cort, A. Yee, F. Liu, M.B. Goshe, A.M. Edwards, and R.D. Smith, et al. 2002. "Myxoma Virus Immunomodulatory Protein M156R is a Structural Mimic of Eukaryotic Translation Initiation Factor eIF2 alpha." Journal of Molecular Biology 322, no. 5:943-954. PNWD-SA-5541.
  • Yee A., X. Chang, A. Pineda-Lucena, B. Wu, A. Semsesi, B. Le, and T.A. Ramelot, et al. 2002. "An NMR Approach to Structural Proteomics." Proceedings of the National Academy of Sciences of the United States of America 99, no. 4:1825-1830. PNWD-SA-5665.


  • Cort J.R., A. Yee, A.M. Edwards, C.H. Arrowsmith, and M.A. Kennedy. 2001. "NMR Structure Determination and Structure-Based Functional Characterization of a Conserved, Hypothetical Protein MTH1175 from Methanobacterium thermoautotrophicum." Journal of Structural and Functional Genomics 1. PNNL-SA-33300.
  • Cort J.R., S.S. Mariappan, C.Y. Kim, M.S. Park, T.S. Peat, G.S. Waldo, and T.C. Terwilliger, et al. 2001. "Solution Structure of Pyrobaculum aerophilum DsrC, an Archaeal Homologue of the Gamma Subunit of Dissimilatory Sulfite Reductase." European Journal of Biochemistry / FEBS 268, no. 22:5842-50. PNWD-SA-5402.


  • Christendat D., A. Yee, A. Dharamsi, Y. Kluger, A. Savchenko, J.R. Cort, and V. Booth, et al. 2000. "Structural Proteomics of an Archaeon." Nature Structural & Molecular Biology 7, no. 10:903-909. PNNL-SA-34008. doi:10.1038/82823
  • Cort J.R., A. Yee, A.M. Edwards, C.H. Arrowsmith, and M.A. Kennedy. 2000. "Structure-Based Functional Classification of Hypothetical Protein MTH538 from Methanobacterium thermoautotrophicum." Journal of Molecular Biology 302, no. 1:189-203. PNNL-SA-33137.


  • Cort J.R., E.V. Koonin, P.A. Bash, and M.A. Kennedy. 1999. "A Phylogenetic Approach to Target Selection for Structural Genomics: Solution Structure of YciH." Nucleic Acids Research 27, no. 20:4018-4027. PNNL-SA-31336.

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