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Staff information

Hans Bernstein

Microbiome Science
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-18
Richland, WA 99352

PNNL Publications


  • Beck A, HC Bernstein, and R Carlson. 2017. "Stoichiometric network analysis of cyanobacterial acclimation to photosynthesis-associated stresses identifies heterotrophic niches." Processes 5(2):Article No. 32.  doi:10.3390/pr5020032
  • Bernstein HC, CJ Brislawn, KL Dana, TM Flores-Wentz, AB Cory, SJ Fansler, JK Fredrickson, and JJ Moran. 2017. "Primary and heterotrophic productivity relate to multi-kingdom diversity in a hypersaline mat." FEMS Microbiology Ecology 93(10):Article No. fix121.  doi:10.1093/femsec/fix121
  • Bernstein HC, CJ Brislawn, RS Renslow, KL Dana, BR Morton, SR Lindemann, HS Song, E Atci, H Beyenal, JK Fredrickson, JK Jansson, and JJ Moran. 2017. "Trade-offs between microbiome diversity and productivity in a stratified microbial mat." The ISME Journal 11(2):405-414.  doi:10.1038/ismej.2016.133
  • Bernstein HC, RS McClure, V Thiel, NC Sadler, YM Kim, WB Chrisler, EA Hill, DA Bryant, MF Romine, JK Jansson, JK Fredrickson, and AS Beliaev. 2017. "Indirect interspecies regulation; transcriptional and physiological responses of a cyanobacterium to heterotrophic partnership." mSystems 2(2):Article No. e00181-16.  doi:10.1128/mSystems.00181-16
  • Hill EA, WB Chrisler, AS Beliaev, and HC Bernstein. 2017. "A flexible microbial co-culture platform for simultaneous utilization of methane and carbon dioxide from gas feedstocks." Bioresource Technology 228:250-256.  doi:10.1016/j.biortech.2016.12.111
  • Mobberley JM, SR Lindemann, HC Bernstein, JJ Moran, RS Renslow, JT Babauta, D Hu, H Beyenal, and WC Nelson. 2017. "Organismal and spatial partitioning of energy and macronutrient transformations within a hypersaline mat." FEMS Microbiology Ecology 93(4):Article No. fix028.  doi:10.1093/femsec/fix028


  • Beam J, HC Bernstein, Z Jay, M Kozubal, R Jennings, SG Tringe, and WP Inskeep. 2016. "Assembly and Succession of Iron Oxide Microbial Mat Communities in Acidic Geothermal Springs." Frontiers in Microbiology 7:Article No. 25.  doi:10.3389/fmicb.2016.00025
  • Beck A, K Hunt, HC Bernstein, and R Carlson. 2016. "Interpreting and designing microbial communities for bioprocess applications, from components to interactions to emergent properties." Chapter 15 in Biotechnologies for Biofuel Production and Optimization, ed. CE Eckert and CT Trinh, pp. 407-432.  Elsevier, Amsterdam, Netherlands.  doi:10.1016/B978-0-444-63475-7.00015-7
  • Bernstein HC, RS McClure, EA Hill, LM Markillie, WB Chrisler, MF Romine, JE McDermott, MC Posewitz, DA Bryant, A Konopka, JK Fredrickson, and AS Beliaev. 2016. "Unlocking the Constraints of Cyanobacterial Productivity: Acclimations Enabling Ultrafast Growth." mBio 7(4):Article No. e00949-16.  doi:10.1128/mBio.00949-16
  • Henry CS, HC Bernstein, P Weisenhorn, RC Taylor, JY Lee, JD Zucker, and HS Song. 2016. "Microbial Community Metabolic Modeling: A Community Data-Driven Network Reconstruction." Journal of Cellular Physiology 231(11):2339-2345.  doi:10.1002/jcp.25428
  • James GA, AG Zhao, M Usui, RA Underwood, HD Nguyen, H Beyenal, E Pulcini, A Agostinho, HC Bernstein, P Fleckman, J Olerud, KS Williamson, MJ Franklin, and PS Stewart. 2016. "Microsensor and transcriptomic signatures of oxygen depletion in biofilms associated with chronic wounds." Wound Repair and Regeneration 24(2):373-383.  doi:10.1111/wrr.12401
  • Lindemann SR, HC Bernstein, HS Song, JK Fredrickson, MW Fields, W Shou, D Johnson, and AS Beliaev. 2016. "ENGINEERING MICROBIAL CONSORTIA FOR CONTROLLABLE OUTPUTS." The ISME Journal 10(2016):2077-2084.  doi:10.1038/ismej.2016.26
  • Sadler NC, HC Bernstein, MR Melnicki, MA Charania, EA Hill, LN Anderson, ME Monroe, RD Smith, AS Beliaev, and AT Wright. 2016. "Dinitrogenase Driven Photobiological Hydrogen Production Combats Oxidative Stress in Cyanothece sp. ATCC 51142." Applied Environmental Microbiology 82(24):7227-7235.  doi:10.1128/AEM.02098-16


  • Bernstein HC, MA Charania, RS McClure, NC Sadler, MR Melnicki, EA Hill, LM Markillie, CD Nicora, AT Wright, MF Romine, and AS Beliaev. 2015. "Multi-omic Dynamics Associate Oxygenic Photosynthesis with Nitrogenase-mediated H2 production in Cyanothece sp. ATCC 51142." Scientific Reports 5:Article No. 16004.  doi:10.1038/srep16004
  • Song HS, RS McClure, HC Bernstein, CC Overall, EA Hill, and AS Beliaev. 2015. "Integrated in silico analyses of regulatory and metabolic networks of Synechococcus sp. PCC 7002 reveal relationships between gene centrality and essentiality." Life 5(2):1127-1140.  doi:10.3390/life5021127


  • Bernstein HC, M Kesaano, K Moll, T Smith, R Gerlach, R Carlson, CD Miller, B Peyton, K Cooksey, RD Gardner, and RC Sims. 2014. "Direct measurement and characterization of active photosynthesis zones inside biofuel producing and wastewater remediating microalgal biofilms." Bioresource Technology 156:206-215.  doi:10.1016/j.biortech.2014.01.001
  • Moran JJ, CG Doll, HC Bernstein, RS Renslow, AB Cory, JR Hutchison, SR Lindemann, and JK Fredrickson. 2014. "Spatially tracking 13C labeled substrate (bicarbonate) accumulation in microbial communities using laser ablation isotope ratio mass spectrometry." Environmental Microbiology Reports 6(6):786-791.  doi:10.1111/1758-2229.12211
  • Beliaev AS, MF Romine, M Serres, HC Bernstein, BE Linggi, LM Markillie, NG Isern, WB Chrisler, LA Kucek, EA Hill, G Pinchuk, DA Bryant, HS Wiley, JK Fredrickson, and A Konopka. 2014. "Inference of Interactions in Cyanobacterial-Heterotrophic Co-Cultures via Transcriptome Sequencing." The ISME Journal 8(11):2243-2255.  doi:10.1038/ismej.2014.69
  • Bernstein HC, A Konopka, MR Melnicki, EA Hill, LA Kucek, S Zhang, G Shen, DA Bryant, and AS Beliaev. 2014. "Effect of mono- and dichromatic light quality on growth rates and photosynthetic performance of Synechococcus sp. PCC 7002." Frontiers in Microbiology 5:Article No. 488.  doi:10.3389/fmicb.2014.00488

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