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Staff information

David

David Koppenaal

Science and Technology
Lab Fellow, Team Lead, Chemist
Pacific Northwest National Laboratory
PO Box 999
MSIN: K8-84
Richland, WA 99352

Biography

Dr. Koppenaal manages the Biological Separations & Mass Spectrometry group within the Biological Sciences Division of the Fundamental & Computational Sciences Directorate at Pacific Northwest National Laboratory. He manages 65 staff members in the development of high-resolution separations and mass spectrometry and their applications in biological research. The current research emphasis is in the area of proteomics - the study of the entire complement of proteins expressed in a cell under a specific set of conditions at a specific time.

Dr. Koppenaal served as interim Chief Research Officer (CRO) for PNNL from June 2006 through September 2007. In the CRO role, Dr. Koppenaal reported to the Laboratory Director and was a member of the upper management team for the Laboratory. Dr. Koppenaal was responsible for the overall science and technology portfolio and capability of the Laboratory, and directed management of the Laboratory's ~$30M discretionary research (LDRD) budget.

From 2003-2006, Dr. Koppenaal managed the Macromolecular Structure and Dynamics group within the Biological Sciences Division. He managed this same group while Associate Director of the W.R. Wiley Environmental Molecular Sciences Laboratory from 1998-2003. This group (~ 40 staff) was active in the development of techniques and methods for proteomics and structural/functional biology. In these roles, Dr. Koppenaal oversaw the development, installation, and commissioning of the world's first wide-bore 900 MHz NMR spectrometry system (at that time the highest field NMR in the world). During this same time, PNNL developed world-class proteomics capability. Dr. Koppenaal had oversight responsibility of the Richard Smith research group at PNNL during this period. This effort involved substantial Laboratory, DOE, and NIH interaction and advocacy to build a internationally recognized, high-throughput proteomics capability.

Research Interests

  • Dr. Koppenaal's recent research includes the development of new types of mass spectrometry instrumentation and MS detectors based on ion-sensitive arrays (in collaboration with colleagues at the University of Arizona and Indiana University). This research may well provide the basis for a truly simultaneous, "all-the-signal, all-the-time" detector for elemental mass spectrometry, and has recently been highlighted in an Analytical Chemistry 'A' page review article. Another recent interest has taken Dr. Koppenaal into the field of metallomics. He helped introduce the elemental analysis community to this emerging new field and is currently active in the development of new high-resolution instrumentation and methods for the characterization of the metallome.
  • Dr. Koppenaal's research has been focused principally on the development of atomic mass spectrometry for inorganic and isotopic characterization, and the demonstration of new analytical techniques and instruments for environmental, nuclear, nonproliferation, and biological/health problems. Dr. Koppenaal's specific expertise in atomic mass spectrometry is recognized internationally. He became involved with the development of this technique in the early 1980s and has been involved in ion source and detector instrumentation, applications, and theoretical innovations with this widely used analytical technology. He and co-workers at Pacific Northwest National Laboratory have pioneered the application of ICP/MS as a powerful and relevant radioanalytical tool and demonstrated its utility for both radioactive waste characterization and its use as an ultra-trace nuclear forensics tool for the nuclear nonproliferation community. These efforts resulted in the building of one of the nation's first glove-box enclosed ICP/MS instruments, demonstration of coupled ion chromatography-ICP/MS, and the use of laser ablation ICP/MS for improved radwaste analysis. Dr. Koppenaal's group also initiated elemental analysis research with ion trap MS based instrumentation in the early 90's. In related work, his group developed gas-phase reaction chemistry approaches that ultimately revolutionized the ICPMS field, resulting in a completely new generation of collision and reaction cell plasma source instruments.

Education and Credentials

  • Ph.D., Chemistry (Analytical). University of Missouri(Columbia), 1978.
  • B.S., Environmental Chemistry and Mathematics (double major). Southwest Missouri State University, 1974.

Awards and Recognitions

  • Elected American Chemical Society Analytical Chemistry Division Chair, 2009
  • Elected Fellow of the American Association for the Advancement of Science in 2007.
  • Elected Fellow of the Royal Society of Chemistry (UK) in 2005.
  • Federal Laboratory Consortium Award for Excellence in Technology Transfer, Inductively Coupled Plasma Mass Spectrometry Collision/Reaction Cell Technology, 2004.
  • Promoted to Laboratory Fellow in 1998 (this position is the highest level of scientific achievement in PNNL).
  • Federal Laboratory Consortium Award for Excellence in Technology Transfer, Plasma Source Ion Trap Mass Spectrometry, 1997.
  • R&D 100 Award, PSQ Plasma Source Mass Spectrometer, 1996.
  • NSF Graduate Research Traineeship, University of Missouri and Pittsburgh Energy Technology Center, 1976-1978.
  • Member of American Chemical Society, Analytical Division; Royal Society of Chemistry (UK); American Society for Mass Spectrometry; American Association for Advancement of Science.
  • Editorial Board Member, Journal of Analytical Atomic Spectroscopy, 2001-present.

PNNL Publications

2018

  • Hoegg E.D., R. Marcus, G.J. Hager, G.L. Hart, and D.W. Koppenaal. 2018. "Concomitant Ion Effects on Isotope Ratio Measurements with Liquid Sampling - Atmospheric Pressure Glow Discharge Ion Source Orbitrap Mass Spectrometry." Journal of Analytical Atomic Spectrometry 33, no. 2:251-259. PNNL-SA-124756. doi:10.1039/C7JA00308K

2017

  • Grate J.W., J.J. Gonzalez, M.J. O'Hara, C.M. Kellogg, S.S. Morrison, D.W. Koppenaal, and G.C. Chan, et al. 2017. "Solid Matrix Transformation and Tracer Addition using Molten Ammonium Bifluoride Salt as a Sample Preparation Method for Laser Ablation Inductively Coupled Plasma Mass Spectrometry." Analyst 142, no. 18:3333-3340. PNNL-SA-124596. doi:10.1039/C7AN00777A
  • Liberton M.L., W.B. Chrisler, C.D. Nicora, R.J. Moore, R.D. Smith, D.W. Koppenaal, and H.B. Pakrasi, et al. 2017. "Phycobilisome Truncation Causes Widespread Proteome Changes in Synechocystis sp. PCC 6803." PLoS One 12, no. 3:e0173251. PNNL-SA-112677. doi:10.1371/journal.pone.0173251
  • Stopka S.A., B.J. Agtuca, D.W. Koppenaal, L. Pasa Tolic, G. Stacey, A. Vertes, and C.R. Anderton. 2017. "Laser Ablation Electrospray Ionization Mass Spectrometry with Ion Mobility Separation Reveals Metabolites and Lipids in the Symbiotic Interactions of Soybean Roots and Rhizobia." The Plant Journal 91, no. 2:340-354. PNNL-SA-121531. doi:10.1111/tpj.13569
  • Walker L.R., M.M. Tfaily, J.B. Shaw, N.J. Hess, L. Pasa Tolic, and D.W. Koppenaal. 2017. "Unambiguous Identification & Discovery of Bacterial Siderophores by Direct Injection 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry." Metallomics 9, no. 1:82-92. PNNL-SA-121375. doi:10.1039/c6mt00201c

2016

  • Hoegg E.D., C.J. Barinaga, G.J. Hager, G.L. Hart, D.W. Koppenaal, and R. Marcus. 2016. "Isotope Ratio Characteristics and Sensitivity for Uranium Determinations Using a Liquid Sampling-Atmospheric Pressure Glow Discharge Ion Source Coupled to an Orbitrap Mass Analyzer." Journal of Analytical Atomic Spectrometry 31, no. 12:2355-2362. PNNL-SA-117726. doi:10.1039/C6JA00163G
  • Hoegg E.D., C.J. Barinaga, G.J. Hager, G.L. Hart, D.W. Koppenaal, and R. Marcus. 2016. "Preliminary Figures of Merit for Isotope Ratio Measurements: The Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Ionization Source Coupled to an Orbitrap Mass Analyzer." Journal of the American Society for Mass Spectrometry 27, no. 8:1393-1403. PNNL-SA-116115. doi:10.1007/s13361-016-1402-4
  • Liberton M.L., R. Saha, J.M. Jacobs, A.Y. Nguyen, M.A. Gritsenko, R.D. Smith, and D.W. Koppenaal, et al. 2016. "Global Proteomic Analysis Reveals an Exclusive Role of Thylakoid Membranes in Bioenergetics of a Model Cyanobacterium." Molecular and Cellular Proteomics 15, no. 6:2021-2032. PNNL-SA-121062. doi:10.1074/mcp.M115.057240
  • Liberton M.L., R. Saha, J.M. Jacobs, A.Y. Nguyen, M.A. Gritsenko, R.D. Smith, and D.W. Koppenaal, et al. 2016. "Proteomics analysis of isolated plasma membrane and thylakoid membrane from Synechocystis sp. PCC 6803." Molecular and Cellular Proteomics 15, no. 6:2021-2032. PNNL-SA-112674. doi:10.1074/mcp.M115.057240
  • Shaw J.B., T. Lin, F.E. Leach, A.V. Tolmachev, N. Tolic, E.W. Robinson, and D.W. Koppenaal, et al. 2016. "21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Greatly Expands Mass Spectrometry Toolbox." Journal of the American Society for Mass Spectrometry 27, no. 12:1929-1936. PNNL-SA-121061. doi:10.1007/s13361-016-1507-9

2015

  • Gundlach-Graham A.W., E. Dennis, S.J. Ray, C.G. Enke, C.J. Barinaga, D.W. Koppenaal, and G.M. Hieftje. 2015. "Laser-ablation sampling for inductively coupled plasma distance-of-flight mass spectrometry." Journal of Analytical Atomic Spectrometry 30, no. 1:139-147. PNNL-SA-109896. doi:10.1039/C4JA00231H
  • Lin T., G.A. Anderson, R.V. Norheim, S.A. Prost, B.L. Lamarche, F.E. Leach, and K.J. Auberry, et al. 2015. "An Adaptable Multiple Power Source for Mass Spectrometry and other Scientific Instruments." Review of Scientific Instruments 86, no. 9:Article No. 094102. PNNL-SA-110063. doi:10.1063/1.4930967
  • Yu J., M.L. Liberton, P. Cliften, R. Head, J.M. Jacobs, R.D. Smith, and D.W. Koppenaal, et al. 2015. "Synechococcus elongatus UTEX 2973, a fast growing cyanobacterial chassis for biosynthesis using light and CO2." Scientific Reports 5. PNNL-SA-105375. doi:10.1038/srep08132

2014

  • Aryal U.K., S.J. Callister, B.H. McMahon, L.A. McCue, J.N. Brown, J. Stockel, and M.L. Liberton, et al. 2014. "Proteomic profiles of five strains of oxygenic photosynthetic cyanobacteria of the genus Cyanothece." Journal of Proteome Research 13, no. 7:3262-3276. PNNL-SA-102687. doi:10.1021/pr5000889
  • Barinaga C.J., G.J. Hager, G.L. Hart, D.W. Koppenaal, R. Marcus, S. Jones, and B.T. Manard. 2014. "Toward a Fieldable Atomic Mass Spectrometer for Safeguards Applications: Sample Preparation and Ionization." In Symposium on International Safeguards: Linking Strategy, Implementation and People, October 20-24, 2014, Vienna, Austria, IAEA-CN-220, Paper No. S08-08. Vienna:International Atomic Energy Agency. PNNL-SA-105990.

2013

  • Aryal U.K., S.J. Callister, S. Mishra, X. Zhang, J.I. Shutthanandan, T.E. Angel, and A.K. Shukla, et al. 2013. "Proteome Analyses of Strains ATCC 51142 and PCC 7822 of the Diazotrophic Cyanobacterium Cyanothece sp under Culture Conditions Resulting in Enhanced H-2 Production." Applied and Environmental Microbiology 79, no. 4:1070-1077. PNNL-SA-90813. doi:10.1128/AEM.02864-12
  • Dennis E., A.W. Gundlach-Graham, C. Enke, S.J. Ray, A.J. Carado, C.J. Barinaga, and D.W. Koppenaal, et al. 2013. "How Constant Momentum Acceleration Decouples Energy and Space Focusing in Distance-of-Flight and Time-of-Flight Mass Spectrometries." Journal of the American Society for Mass Spectrometry 24, no. 5:690-700. PNNL-SA-91012. doi:10.1007/s13361-013-0587-z
  • Dennis E., S.J. Ray, A.W. Gundlach-Graham, C.G. Enke, C.J. Barinaga, D.W. Koppenaal, and G.M. Hieftje. 2013. "Constant-Momentum Acceleration Time-of-Flight Mass Spectrometry with Energy Focusing." Journal of the American Society for Mass Spectrometry 24, no. 12:1853-1861. PNNL-SA-97963. doi:10.1007/s13361-013-0723-9
  • Gundlach-Graham A.W., E. Dennis, S.J. Ray, C.G. Enke, C.J. Barinaga, D.W. Koppenaal, and G.M. Hieftje. 2013. "First inductively coupled plasma-distance-of-flight mass spectrometer: instrument performance with a microchannel plate/phosphor imaging detector." Journal of Analytical Atomic Spectrometry 28, no. 9:1385-1395. PNNL-SA-97822. doi:10.1039/c3ja50122a
  • Gundlach-Graham A.W., E. Dennis, S.J. Ray, C.G. Enke, C.J. Barinaga, D.W. Koppenaal, and G.M. Hieftje. 2013. "Interleaved Distance of Flight Mass Spectrometry: A Simple Method to Improve Instrument Duty Factor." Journal of the American Society for Mass Spectrometry 24, no. 11:1736-1744. PNNL-SA-96414. doi:10.1007/s13361-013-0718-6

2012

  • Aryal U.K., J. Stockel, E.A. Welsh, M.A. Gritsenko, C.D. Nicora, D.W. Koppenaal, and R.D. Smith, et al. 2012. "Dynamic proteome analysis of Cyanothece sp. ATCC 51142 under constant light." Journal of Proteome Research 11, no. 2:609-619. PNNL-SA-80375. doi:10.1021/pr200959x
  • Carado A.J., C. Quarles, A.M. Duffin, C.J. Barinaga, R. Russo, R. Marcus, and G.C. Eiden, et al. 2012. "Femtosecond Laser Ablation Particle Introduction to a Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source." Journal of Analytical Atomic Spectrometry 27, no. 3:385-389. PNNL-SA-84012. doi:10.1039/C2JA10331A
  • Eiden G.C., C.J. Barinaga, and D.W. Koppenaal. 2012. "Reduction of polyatomic interferences in ICP-MS by collision/reaction cell (CRC-ICP-MS) techniques." In ENCYCLOPEDIA OF MASS SPECTROMETRY: ELEMENTAL AND ISOTOPE RATIO MASS SPECTROMETRY, edited by D Beauchemin and DE Matthews. 122-131. Waltham, Massachusetts:Elsevier Science. PNNL-SA-45375.
  • Enke C., S.J. Ray, A.W. Graham, E. Dennis, G.M. Hieftje, A.J. Carado, and C.J. Barinaga, et al. 2012. "Distance-of-Flight Mass Spectrometry: A New Paradigm for Mass Separation and Detection." Annual Review of Analytical Chemistry 5, no. 5:487-504. PNNL-SA-82853. doi:10.1146/annurev-anchem-091411-121050
  • Gundlach-Graham A.W., E. Dennis, S.J. Ray, C.G. Enke, A.J. Carado, C.J. Barinaga, and D.W. Koppenaal, et al. 2012. "Extension of the Focusable Mass Range in Distance-of-Flight Mass Spectrometry with Multiple Detectors." Rapid Communications in Mass Spectrometry 26, no. 21:2526-2534. PNNL-SA-90209. doi:10.1002/rcm.6379
  • Quarles C., A.J. Carado, C.J. Barinaga, D.W. Koppenaal, and R. Marcus. 2012. "Liquid Sampling-Atmospheric Pressure Glow Discharge (LS-APGD) Ionization Source for Elemental Mass Spectrometry: Preliminary Parametric Evaluation and Figures of Merit." Analytical and Bioanalytical Chemistry 402, no. 1:261-268. PNNL-SA-82307. doi:10.1007/s00216-011-5359-7
  • Thevuthasan S., J.E. Evans, L.J. Terminello, D.W. Koppenaal, K.L. Manke, and C. Plata. 2012. Compact X-ray Light Source Workshop Report. PNNL-22145. Richland, WA: Pacific Northwest National Laboratory.

2011

  • Ahring B.K., N.S. Baliga, J.R. Frederickson, S. Kaplan, H.B. Pakrasi, J.G. Pounds, and I. shah, et al. 2011. Biological Interactions and Dynamics Science Theme Advisory Panel (BID-STAP). PNNL-20717. Richland, WA: Pacific Northwest National Laboratory.
  • Aryal U.K., J. Stockel, R.K. Krovvidi, M.A. Gritsenko, M.E. Monroe, R.J. Moore, and D.W. Koppenaal, et al. 2011. "Dynamic proteomic profiling of a unicellular cyanobacterium Cyanothece ATCC51142 across light-dark diurnal cycles." BMC Systems Biology 5. PNNL-SA-81418. doi:10.1186/1752-0509-5-194
  • Graham A.W., S.J. Ray, C.G. Enke, C.J. Barinaga, D.W. Koppenaal, and G.M. Hieftje. 2011. "First Distance-of-Flight Instrument: Opening A New Paradigm in Mass Spectrometry." Journal of the American Society for Mass Spectrometry 22, no. 1:110-117. PNNL-SA-73224. doi:10.1007/s13361-010-0005-8
  • Graham A.W., S.J. Ray, C.G. Enke, J.A. Felton, A.J. Carado, C.J. Barinaga, and D.W. Koppenaal, et al. 2011. "Resolution and Mass Range Performance in Distance-of-Flight Mass Spectrometry with a Multichannel Focal-Plane Camera Detector." Analytical Chemistry 83, no. 22:8552-8559. PNNL-SA-83410. doi:10.1021/ac201876y
  • Graham A.W., S.J. Ray, C.G. Enke, J.A. Felton, A.J. Carado, C.J. Barinaga, and D.W. Koppenaal, et al. 2011. "Resolution and Mass Range Performance in Distance-of-flight Mass Spectrometry with a Multichannel Focal-Plane Camera Detector." Analytical Chemistry 83, no. 22:8552-8559. PNNL-SA-84240. doi:10.1021/ac201876y
  • Marcus R., C. Quarles, C.J. Barinaga, A.J. Carado, and D.W. Koppenaal. 2011. "Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source for Elemental Mass Spectrometry." Analytical Chemistry 83, no. 7:2425-2429. PNNL-SA-77552. doi:10.1021/ac200098h
  • Stockel J., J.M. Jacobs, T.R. Elvitigala, M.L. Liberton, E.A. Welsh, A.D. Polpitiya, and M.A. Gritsenko, et al. 2011. "Diurnal Rhythms Result in Significant Changes in the Cellular Protein Complement in the Cyanobacterium Cyanothece 51142." PLoS One 6, no. 2:Article No.: e16680. PNNL-SA-78209. doi:10.1371/journal.pone.0016680

2010

  • Felton J.A., G.D. Schilling, S.J. Ray, R.P. Sperline, M.B. Denton, C.J. Barinaga, and D.W. Koppenaal, et al. 2010. "Evaluation of a fourth-generation focal plane camera for use in plasma-source mass spectrometry." Journal of Analytical Atomic Spectrometry 26, no. 2:300-304. PNNL-SA-78133. doi:10.1039/c0ja00087f
  • Rubinshtein A.A., G.D. Schilling, S.J. Ray, R.P. Sperline, B.M. Denton, C.J. Barinaga, and D.W. Koppenaal, et al. 2010. "Characterization of a third-generation Faraday-strip array detector coupled to a Mattauch-Herzog geometry mass spectrograph with a dc-glow discharge ionization source." Journal of Analytical Atomic Spectrometry 25, no. 5:735-738. PNNL-SA-72552. doi:10.1039/b913118c

2009

  • Schilling G.D., J.T. Shelley, J. Broekaert, R.P. Sperline, M.B. Denton, C.J. Barinaga, and D.W. Koppenaal, et al. 2009. "Use of an ambient ionization flowing atmospheric-pressure afterglow source for elemental analysis through hydride generation." Journal of Analytical Atomic Spectrometry 24, no. 1:34-40. PNNL-SA-63182.
  • Schilling G.D., S.J. Ray, A.A. Rubinshtein, J. Felton, R.P. Sperline, B.M. Denton, and C.J. Barinaga, et al. 2009. "Evaluation of a 512-Channel Faraday-Strip Array Detector Coupled to an Inductively Coupled Plasma Mattauch-Herzog Mass Spectrograph." Analytical Chemistry 81, no. 13:5467-5473. PNNL-SA-67740.

2007

  • Koppenaal D.W., and G.M. Hieftje. 2007. "Metallomics - An Interdisciplinary and Evolving Field." Journal of Analytical Atomic Spectrometry 22, no. 8:855. PNNL-SA-57071. doi:10.1039/b710205b
  • Koppenaal D.W., and G.M. Hieftje. 2007. "Metallomics - The Future of Atomic Spectroscopy?." Journal of Analytical Atomic Spectrometry 22, no. 2:111. PNNL-SA-53601. doi:10.1039/b618394h
  • Koropatkin N.M., D.W. Koppenaal, H.B. Pakrasi, and T.J. Smith. 2007. "The Structure of a Cyanobacterial Bicarbonate Transport Protein, CmpA." Journal of Biological Chemistry 282, no. 4:2606-2614. PNNL-SA-52280. doi:10.1074/jbc.M610222200
  • Schilling G.D., F.J. Andrade, J.H. Barnes IV., R.P. Sperline, M.B. Denton, C.J. Barinaga, and D.W. Koppenaal, et al. 2007. "Continuous Simultaneous Detection in Mass Spectrometry." Analytical Chemistry 79, no. 20:7662-7668. PNNL-SA-55354. doi:10.1021/ac070785s

2006

  • Koppenaal D.W. 2006. "JAAS - 20 Years of Manuscripts, Citations, and Scientific Impact." Journal of Analytical Atomic Spectrometry 21, no. 3:259-262. PNNL-SA-48581. doi:10.1039/b601801g
  • Peschel B.U., F.J. Andrade, W.C. Wetzel, G.D. Schilling, G.M. Hieftje, J. Broekaert, and R. Sperline, et al. 2006. "Electrothermal vaporization coupled with inductively coupled plasma array-detector mass spectrometry for the multielement analysis of Al2O3 ceramic powders." Spectrochimica Acta. Part B, Atomic Spectroscopy 61, no. 1:42-49. PNNL-SA-46498.
  • Schilling G.D., F.J. Andrade, J.H. Barnes, R.P. Sperline, M.B. Denton, C.J. Barinaga, and D.W. Koppenaal, et al. 2006. "Characterization of a Second-generation Focal-plane Camera Coupled to an Inductively Coupled Plasma Mattauch-Herzog Geometry Mass Spectrograph." Analytical Chemistry 78, no. 13:4319-4325. PNNL-SA-51209.

2005

  • Koppenaal D.W., C.J. Barinaga, M.B. Denton, R.P. Sperline, G.M. Hieftje, G.D. Schilling, and F.J. Andrade, et al. 2005. "MS Detectors." Analytical Chemistry 77, no. 21:418A-427A. PNNL-SA-45638.
  • Sperline R.P., A.K. Knight, C.A. Gresham, D.W. Koppenaal, G.M. Hieftje, and M.B. Denton. 2005. "Read-Noise Characterization of Focal Plane Array Detectors via Mean-Variance Analysis." Applied Spectroscopy 59, no. 11:1315-1323. PNNL-SA-46926.

2004

  • Barnes J.H., G. Schilling, R. Sperline, M.B. Denton, E.t. Young, C.J. Barinaga, and D.W. Koppenaal, et al. 2004. "Characterization of a Focal Plane Camera Fittted to a Mattauch-Herzog Geometry Mass Spectrograph. 2. Use with an Inductively Coupled Plasma." Analytical Chemistry 76, no. 9:2531-2536. PNNL-SA-42139.
  • Barnes J.H., G. Schilling, R. Sperline, M.B. Denton, E.t. Young, C.J. Barinaga, and D.W. Koppenaal, et al. 2004. "Coupling of a gas chromatograph to a simultaneous-detection inductively coupled plasma mass spectrograph for speciation of organohalide and organometallic compounds." Journal of Analytical Atomic Spectrometry 19, no. 6:751-756. PNNL-SA-41733.
  • Barnes J.H., G.D. Schilling, G.M. Hieftje, R.P. Sperline, M.B. Denton, C.J. Barinaga, and D.W. Koppenaal. 2004. "Use of a Novel Array Detector for the Direct Analysis of Solid Samples by Laser Ablation Inductively Coupled Plasma Sector-Field Mass Spectrometry." Journal of the American Society for Mass Spectrometry 15, no. 6:769-776. PNNL-SA-40984.
  • Barnes J.H., G.D. Schilling, S.F. Stone, R.P. Sperline, M.B. Denton, E.t. Young, and C.J. Barinaga, et al. 2004. "Simultaneous multichannel mass-specific detention for high-performance liquid chromatography using an array detector sector-field mass spectrometer." Analytical and Bioanalytical Chemistry 380, no. 2:227-234. PNNL-SA-44402.
  • Koppenaal D.W., and G.C. Eiden. 2004. "Foreword: Collision and reaction cell techniques in atomic mass spectrometry." Journal of Analytical Atomic Spectrometry 19, no. 5:15N. PNNL-SA-41475.
  • Koppenaal D.W., G.C. Eiden, and C.J. Barinaga. 2004. "Collision and reaction cells in atomic mass spectrometry: development, status, and applications." Journal of Analytical Atomic Spectrometry 19, no. 5:561-570. PNNL-SA-41473.

2003

  • Barnes IV. J.H., G. Schilling, M. Denton, D.W. Koppenaal, and G.M. Hieftje. 2003. "Development and characterization of an electrostatic quadrupole extraction lens for mass spectrometry." Journal of Analytical Atomic Spectrometry 18, no. 9:1015-1018. PNNL-SA-39173.
  • Barnes J.H., G.M. Hieftje, M. Denton, R. Sperline, D.W. Koppenaal, and C.J. Barinaga. 2003. "A Mass Spectrometry Detector Array That Provides Truly Simultaneous Detection." American Laboratory 35, no. 20:15-22. PNNL-SA-40184.

2002

  • Barnes Iv. J.H., R. Sperline, M. Denton, C.J. Barinaga, D.W. Koppenaal, E.t. Young, and G.M. Hieftje. 2002. "Characterization of a Focal Plane Camera Fitted to a Mattauch-Herzog Geometry Mass Spectrograph. 1. Use with a Glow-Discharge Source." Analytical Chemistry 74, no. 20:5327-5332. PNNL-SA-37580.
  • Hieftje G.M., J.H. Barnes, O.A. Gron, A.M. Leach, D.M. Mcclenathan, S.J. Ray, and D.A. Solyom, et al. 2002. "Evolution and Revolution in Instrumentation for Plasma-Source Mass Spectrometry." Pure and Applied Chemistry 73, no. 10:1579-1588. PNNL-SA-35586.
  • Knight A.K., R.P. Sperline, G.M. Hiefje, E. Young, C.J. Barinaga, D.W. Koppenaal, and M.B. Denton. 2002. "The Development of a Micro-Faraday-Array for Ion Detection." International Journal of Mass Spectrometry and Ion Processes 215, no. (1-3 SP ISS):131-139. PNNL-SA-35585.

2001

  • Henry R., D. Koller, M. Liezers, O.T. Farmer, C.J. Barinaga, D.W. Koppenaal, and J.F. Wacker. 2001. "New advances in inductively coupled plasma-mass spectrometry (ICP-MS) for routine measurements in the nuclear industry." Journal of Radioanalytical and Nuclear Chemistry 249, no. 1:103-108. PNNL-SA-35979.
  • Koppenaal D.W., P.D. Ellis, and R.D. Smith. 2001. Annual Report 2000 Macromolecular Structure and Dynamics. PNNL-13626. Richland, WA: Pacific Northwest National Laboratory.

1999

  • Eiden G.C., C.J. Barinaga, and D.W. Koppenaal. 1999. "Analytical Performance of the Plasma Source RF Quadrupole Ion Trap in Elemental and Isotopic MS." Journal of Analytical Atomic Spectrometry 14, no. 8:1129-1132. PNWD-SA-4594.
  • Koppenaal D.W., E.J. Wyse, C.W. Lindenmeier, and J.P. Bramson. 1999. "Actinides in Biological and Environmental Systems." Journal of Radioanalytical and Nuclear Chemistry 234. PNNL-SA-31581.

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