Skip to Main Content U.S. Department of Energy
Science Directorate
Page 203 of 559

Biological Sciences Division

September 2013

Cort, Metaxas Research Featured in Chemical & Engineering News

John Cort
John Cort

Research by Pacific Northwest National Laboratory scientist Dr. John R. Cort and PNNL undergraduate summer intern Athena E. Metaxas was highlighted by Chemical & Engineering News reporter Carmen Drahl in the September 16 issue. "NMR Method Can Chase Down Chemical Threats," described the researchers' use of nuclear magnetic resonance spectroscopy to clearly distinguish different salt forms of the highly toxic alkaloid strychnine from one another based on the way different counterions such as chloride or sulfate influence the NMR spectra.

The ability to associate chemicals with their source or with other samples having a common origin is fundamental to the establishment of attribution signatures for chemical forensics. This method may be applicable to other organic compounds of interest that commonly exist as two or more distinct salt forms, including many pesticides, counterfeit pharmaceuticals, illicit drugs, and biological toxins.

Reference: Metaxas AE and JR Cort. 2013. "Counterion Influence on Chemical Shifts in Strychnine Salts." Magnetic Resonance in Chemistry 51(5):292-298. DOI: 10.1002/mrc.3945.

Page 203 of 559

Science at PNNL

Core Research Areas

User Facilities

Centers & Institutes

Additional Information

Research Highlights Home


Print this page (?)

YouTube Facebook Flickr TwitThis LinkedIn