A multi-institution research team found how the protein environment surrounding some enzymes can alter the direction of a cellular reaction, as well as its rate—up to six orders of magnitude—in a phenomenon referred to as catalytic bias.
At PNNL, subsurface science inhabits two separate but interlocking worlds. One looks at basic science, the other at applied science and engineering. Both are funded by the U.S. Department of Energy (DOE).
The world’s largest scientific society honored Sue B. Clark, a PNNL and WSU chemist, for contributions toward resolving our legacy of radioactive waste, advancing nuclear safeguards, and developing landmark nuclear research capabilities.
A radioactive chemical called pertechnetate is a bad actor when it’s in nuclear waste tanks. But researchers at PNNL and the University of South Florida have a new lead on how to selectively separate it from the nuclear waste for treatment.
PNNL scientists have taken one of the most in-depth looks ever at the riot of protein activity that underlies colon cancer and have identified potential new molecular targets to try to stop the disease.
Installing new access holes (up to 6 feet in diameter) could reduce the overall time and cost to retrieve waste from Hanford's underground storage tanks, according to a structural analysis of the tank domes by PNNL and Becht Engineering.