A multi-institution research team found how the protein environment surrounding some enzymes can alter the direction of a cellular reaction, as well as its rate—up to six orders of magnitude—in a phenomenon referred to as catalytic bias.
At PNNL, subsurface science inhabits two separate but interlocking worlds. One looks at basic science, the other at applied science and engineering. Both are funded by the U.S. Department of Energy (DOE).
The world’s largest scientific society honored Sue B. Clark, a PNNL and WSU chemist, for contributions toward resolving our legacy of radioactive waste, advancing nuclear safeguards, and developing landmark nuclear research capabilities.
Researchers apply numerical simulations to understand more about a sturdy material and how its basic structure responds to and resists radiation. The outcomes could help guide development of the resilient materials of the future.
PNNL scientists have taken one of the most in-depth looks ever at the riot of protein activity that underlies colon cancer and have identified potential new molecular targets to try to stop the disease.