Researchers from PNNL have helped colleagues at OHSU identify lipid molecules required for Zika infection in human cells. The specific lipids involved could also be a clue to why the virus primarily infects brain tissue.
A multi-institution research team found how the protein environment surrounding some enzymes can alter the direction of a cellular reaction, as well as its rate—up to six orders of magnitude—in a phenomenon referred to as catalytic bias.
At PNNL, subsurface science inhabits two separate but interlocking worlds. One looks at basic science, the other at applied science and engineering. Both are funded by the U.S. Department of Energy (DOE).
The world’s largest scientific society honored Sue B. Clark, a PNNL and WSU chemist, for contributions toward resolving our legacy of radioactive waste, advancing nuclear safeguards, and developing landmark nuclear research capabilities.
PNNL scientists have taken one of the most in-depth looks ever at the riot of protein activity that underlies colon cancer and have identified potential new molecular targets to try to stop the disease.