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Human Proteome Organization honors PNNL scientist

Dick Smith recognized for advancements in proteomics technologies

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September 30, 2009 Share This!

  • Battelle Fellow Dick Smith with a second-generation instrument that incorporates ion-mobility separation with time-of-flight mass spectrometry.

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TORONTO — Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized for his many accomplishments in pioneering the development of proteomics tools. Scientists use these instruments to study the array of proteins and related molecules that make up much of human blood and tissues.

The Human Proteome Organization, or HUPO, honored Smith with its annual Discovery Award. HUPO is an international scientific organization dedicated to promoting proteomics. As the workhorses of cells, proteins take the instructions coded in a chromosome's genes and turn them into a functioning organism. Proteomics seeks to understand what proteins are functioning in healthy tissues — and when — and how dysfunction leads to disease. Proteomics researchers want to use this information to enable both better detection of diseases and to understand what is needed to develop better cures.

In receiving this award, Smith gave a special address to the 8th Annual HUPO World Congress on Proteomics and Human Health: Environment and Disease. In his presentation, Smith described some of the proteomics developments that earned him this recognition, concluding with a description of a new platform that analyzes samples at least ten times faster than its predecessor. Smith has received dozens of patents while leading the creation of these instruments that can separate and identify proteins and other molecules with higher sensitivity, accuracy and resolution for biological and biomedical applications.

Smith leads a team of a couple dozen physicists, biochemists, engineers and computer scientists at PNNL and EMSL, DOE's Environmental Molecular Sciences Laboratory on PNNL's campus. Their instruments are based on separation methods that include liquid chromatography and ion mobility in combination with mass spectrometry.

 

Tags: Environment, Fundamental Science, EMSL, Mass Spectrometry and Separations, Proteomics

EMSL LogoEMSL, the Environmental Molecular Sciences Laboratory, is a DOE Office of Science user facility. Located at Pacific Northwest National Laboratory in Richland, Wash., EMSL offers an open, collaborative environment for scientific discovery to researchers around the world. Its integrated computational and experimental resources enable researchers to realize important scientific insights and create new technologies. Follow EMSL on Facebook, LinkedIn and Twitter.

PNNL LogoPacific Northwest National Laboratory is the nation's premier laboratory for scientific discovery in chemistry, earth sciences, and data analytics and for solutions to the nation's toughest challenges in energy resiliency and national security. Founded in 1965, PNNL is operated by Battelle for the U.S. Department of Energy's Office of Science. DOE's Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, visit PNNL's News Center. Follow us on FacebookInstagram, LinkedIn and Twitter.

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