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Biological Sciences Staff information

Ryan Renslow

Computational Biology
Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-18
Richland, WA 99352
509/375-6418

Biography

WSU Faculty - Renslow

Ryan Renslow's research focuses on the relationship between microbial community structure and function, the emergence of higher order properties in multispecies communities, and the identification of novel metabolites in these communities. To achieve this, Dr. Renslow uses a suite of computational and mathematical tools, as well as advanced imaging techniques. Applications of his work have intersected human health, energy production, ecology, national defense, machine vision, and biotechnology research areas.

Education and Credentials

  • Postdoc, Linus Pauling Distinguished Postdoctoral Fellow - Pacific Northwest National Laboratory - 2015
  • Ph.D., Chemical Engineering - Washington State University - 2012

Affiliations and Professional Service

  • Adjunct Professor - The Gene and Linda Voiland School of Chemical Engineering and Bioengineering, Washington State University

PNNL Publications

2017

  • Renslow RS, MJ Marshall, AE Tucker, WB Chrisler, and XY Yu. 2017. "In situ nuclear magnetic resonance microimaging of live biofilms in a microchannel." Analyst 142(13):2363-2371.  doi:10.1039/C7AN00078B
  • Bernstein HC, CJ Brislawn, RS Renslow, KL Dana, BR Morton, SR Lindemann, HS Song, E Atci, H Beyenal, JK Fredrickson, JK Jansson, and JJ Moran. 2017. "Trade-offs between microbiome diversity and productivity in a stratified microbial mat." The ISME Journal 11(2):405-414.  doi:10.1038/ismej.2016.133
  • Butler M, HS Mehta, Y Chen, PN Reardon, RS Renslow, M Khbeis, D Irish, and KT Mueller. 2017. "Toward high-resolution NMR spectroscopy of microscopic liquid samples." Physical Chemistry Chemical Physics. PCCP 19(22):14256-14261.  doi:10.1039/c7cp01933e
  • Dunn JR, RS Renslow, JB Cliff, III, and CR Anderton. 2017. "NanoSIMS for Biological Applications: Current Practices and Analyses." Biointerphases 13(3):Article No. 03B301.  doi:10.1116/1.4993628
  • Ma J, CP Casey, X Zheng, YM Ibrahim, CS Wilkins, RS Renslow, DG Thomas, SH Payne, ME Monroe, RD Smith, JG Teeguarden, EM Baker, and TO Metz. 2017. "PIXiE: An Algorithm for Automated Ion Mobility Arrival Time Extraction and Collision Cross Section Calculation using Global Data Association." Bioinformatics 33(17):2715-2722.  doi:10.1093/bioinformatics/btx305
  • Metz TO, EM Baker, EL Schymanski, RS Renslow, DG Thomas, TJ Causon, IK Webb, S Hann, RD Smith, and JG Teeguarden. 2017. "Integrating Ion Mobility Spectrometry into Mass Spectrometry-based Exposome Measurements: What Can It Add and How Far Can It Go?" Bioanalysis 9(1):81-98.  doi:10.4155/bio-2016-0244
  • Mobberley JM, SR Lindemann, HC Bernstein, JJ Moran, RS Renslow, JT Babauta, D Hu, H Beyenal, and WC Nelson. 2017. "Organismal and spatial partitioning of energy and macronutrient transformations within a hypersaline mat." FEMS Microbiology Ecology 93(4):Article No. fix028.  doi:10.1093/femsec/fix028
  • Zheng X, RS Renslow, MM Makola, IK Webb, L Deng, DG Thomas, N Govind, YM Ibrahim, MM Kabanda, IA Dubery, HM Heyman, RD Smith, NE Madala, and EM Baker. 2017. "Structural Elucidation of cis/trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry." The Journal of Physical Chemistry Letters 8(7):1381-1388.  doi:10.1021/acs.jpclett.6b03015
  • Zheng X, X Zhang, N Schocker, RS Renslow, DJ Orton, J Khamsi, RA Ashmus, IC Almeida, K Tang, CE Costello, RD Smith, K Michael, and EM Baker. 2017. "Enhancing Glycan Isomer Separations with Metal Ions and Positive and Negative Polarity Ion Mobility Spectrometry-Mass Spectrometry Analyses." Analytical and Bioanalytical Chemistry 409:467-476.  doi:10.1007/s00216-016-9866-4

2016

  • Renslow RS, SR Lindemann, and HS Song. 2016. "A generalized spatial measure for resilience of microbial systems." Frontiers in Microbiology 7:Article No. 443.  doi:10.3389/fmicb.2016.00443
  • Graham T, RS Renslow, N Govind, and SR Saunders. 2016. "Precursor Ion-Ion Aggregation in the Brust-Schiffrin Synthesis of Alkanethiol Nanoparticles." Journal of Physical Chemistry C 120(35):19837-19847.  doi:10.1021/acs.jpcc.6b06155
  • Renslow RS, SR Lindemann, JK Cole, Z Zhu, and CR Anderton. 2016. "Quantifying element incorporation in multispecies biofilms using nanoscale secondary ion mass spectrometry image analysis." Biointerphases 11(2):02A322.  doi:10.1116/1.4941764
  • Zhang X, MV Romm, X Zheng, EM Zink, YM Kim, KE Burnum-Johnson, DJ Orton, A Apffel, YM Ibrahim, ME Monroe, RJ Moore, JN Smith, J Ma, RS Renslow, DG Thomas, A Blackwell, G Swinford, J Sausen, RT Kurulugama Lekamlage, N Eno, E Darland, G Stafford, JC Fjeldsted, TO Metz, JG Teeguarden, RD Smith, and ES Baker. 2016. "SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in bio?uids." Clinical Mass Spectrometry 2:1-10.  doi:10.1016/j.clinms.2016.11.002

2015

  • Renslow RS, JT Babauta, AP Kuprat, J Schenk, C Ivory, JK Fredrickson, and H Beyenal. 2015. "MATHEMATICAL MODELING OF EXTRACELLULAR ELECTRON TRANSFER IN BIOFILMS." Chapter 9 in Biofilms in Bioelectrochemical Systems: From Laboratory Practice to Data Interpretation.  John Wiley & Sons, Inc., HOBOKEN, NJ.  doi:10.1002/9781119097426.ch9
  • Ha PT, RS Renslow, E Atci, PN Reardon, SR Lindemann, JK Fredrickson, DR Call, and H Beyenal. 2015. "Regulation of electron transfer processes affects phototrophic mat structure and activity." Frontiers in Microbiology 6:Article No. 909.  doi:10.3389/fmicb.2015.00909
  • Harrington TD, JT Babauta, EK Davenport, RS Renslow, and H Beyenal. 2015. "Excess Surface Area in Bioelectrochemical Systems Causes ion Transport Limitations." Biotechnology and Bioengineering 112(5):858-866.  doi:10.1002/bit.25500
  • Harrington TD, VN Tran, A Mohamed, RS Renslow, S Biria, L Orfe, DR Call, and H Beyenal. 2015. "The mechanism of neutral red-mediated microbial electrosynthesis in Escherichia coli: menaquinone reduction." Bioresource Technology 192:689-695.  doi:10.1016/j.biortech.2015.06.037
  • Lone AG, E Atci, RS Renslow, H Beyenal, S Noh, B Fransson, N Abu-Lail, JJ Park, DR Gang, and DR Call. 2015. "Colonization of epidermal tissue by Staphylococcus aureus produces localized hypoxia and stimulates secretion of antioxidant and caspase-14 proteins." Infection and Immunity 83(8):3026-3034.  doi:10.1128/IAI.00175-15
  • Lone AG, E Atci, RS Renslow, H Beyenal, S Noh, B Fransson, N Abu-Lail, JJ Park, DR Gang, and DR Call. 2015. "Staphylococcus aureus induces hypoxia and cellular damage in porcine dermal explants." Infection and Immunity 8(6):2531-2541.  doi:10.1128/IAI.03075-14
  • Song HS, RS Renslow, JK Fredrickson, and SR Lindemann. 2015. "Integrating ecological and engineering concepts of resilience in microbial communities." Frontiers in Microbiology 6:Article No. 1298.  doi:10.3389/fmicb.2015.01298

2014

  • Renslow RS, JT Babauta, PD Majors, HS Mehta, RJ Ewing, T Ewing, KT Mueller, and H Beyenal. 2014. "A biofilm microreactor system for simultaneous electrochemical and nuclear magnetic resonance techniques." Water Science and Technology 69(5):966-973.  doi:10.2166/wst.2013.802
  • Resat H, RS Renslow, and H Beyenal. 2014. "Reconstruction of biofilm images: combining local and global structural parameters." Biofouling 30(9):1141-1154.  doi:10.1080/08927014.2014.969721
  • Cole JK, JR Hutchison, RS Renslow, YM Kim, WB Chrisler, HE Engelmann, A Dohnalkova, D Hu, TO Metz, JK Fredrickson, and SR Lindemann. 2014. "Phototrophic Biofilm Assembly in Microbial-Mat-Derived Unicyanobacterial Consortia: Model Systems for the Study of Autotroph-Heterotroph Interactions." Frontiers in Microbiology 5:Article No. 109.  doi:10.3389/fmicb.2014.00109
  • Moran JJ, CG Doll, HC Bernstein, RS Renslow, AB Cory, JR Hutchison, SR Lindemann, and JK Fredrickson. 2014. "Spatially tracking 13C labeled substrate (bicarbonate) accumulation in microbial communities using laser ablation isotope ratio mass spectrometry." Environmental Microbiology Reports 6(6):786-791.  doi:10.1111/1758-2229.12211

2013

  • Renslow RS, JT Babauta, AP Kuprat, J Schenk, C Ivory, JK Fredrickson, and H Beyenal. 2013. "Modeling biofilms with dual extracellular electron transfer mechanisms." Physical Chemistry Chemical Physics. PCCP 15(44):19262-19283.  doi:10.1039/c3cp53759e
  • Renslow RS, JT Babauta, PD Majors, and H Beyenal. 2013. "Diffusion in biofilms respiring on electrodes." Energy and Environmental Science 6(2):595-607.  doi:10.1039/C2EE23394K
  • Renslow RS, JT Babauta, A Dohnalkova, MI Boyanov, KM Kemner, PD Majors, JK Fredrickson, and H Beyenal. 2013. "Metabolic spatial variability in electrode-respiring Geobacter sulfurreducens biofilms." Energy & Environmental Science 6(6):1827-1836.  doi:10.1039/c3ee40203g
  • Lindemann SR, JJ Moran, JC Stegen, RS Renslow, JR Hutchison, JK Cole, A Dohnalkova, J Tremblay, K Singh, S Malfatti, F Chen, S Tringe, H Beyenal, and JK Fredrickson. 2013. "The Epsomitic Phototrophic Microbial Mat of Hot Lake, Washington: Community Structural Responses to Seasonal Cycling." Frontiers in Microbiology 4:323.  doi:10.3389/fmicb.2013.00323

2012

  • Cao B, PD Majors, B Ahmed, RS Renslow, CP Sylvia, L Shi, S Kjelleberg, JK Fredrickson, and H Beyenal. 2012. "Biofilm Shows Spatially Stratified Metabolic Responses to Contaminant Exposure." Environmental Microbiology 14(11):2901-2910.  doi:10.1111/j.1462-2920.2012.02850.x

2010

  • Renslow RS, PD Majors, JS McLean, JK Fredrickson, B Ahmed, and H Beyenal. 2010. "In Situ Effective Diffusion Coefficient Profiles in Live Biofilms Using Pulsed-Field Gradient Nuclear Magnetic Resonance." Biotechnology and Bioengineering 106(6):928-937. 

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