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Biological Sciences



Aypar U, WF Morgan, and JE Baulch. 2011. "Radiation-Induced Epigenetic Alterations after Low and High LET Irradiations." Mutation Research 707:24-33.

Aypar U, WF Morgan, and JE Baulch. 2011. "Radiation-Induced Genomic Instability: Are Epigenetic Mechanisms the Missing Link?" International Journal of Radiation Research 87:171-191.

Feinendegen LE, AL Brooks, and WF Morgan. 2011. "Biological Consequences and Health Risks of Low-level Exposure to Ionizing Radiation: Commentary on the Workshop." Health Physics 97:426-432.

Kim YM, TO Metz, Z Hu, SD Wiedner, JS Kim, RD Smith, WF Morgan, and Q Zhang. 2011. "Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics." Rapid Communications in Mass Spectrometry 25:2561-2564. doi:10.1002/rcm.5134.

Miller JH, WB Chrisler, X Wang, and MB Sowa. 2011. "Confocal Microscopy for Modeling Electron Microbeam Irradiation of Skin." Radiation and Environmental Biophysics 50(3):365-369. DOI: 10.1007/s00411-011-0371-z.

Miller JH, A Suleiman, WB Chrisler, and MB Sowa. 2011. "Simulation of Electron-Beam Irradiation of Skin Tissue Model." Radiation Research 175(1):113-118.

Morgan WF. 2011. "Communication Non-Targeted Effects of Ionizing Radiation to Achieve Adaptive Homeostasis in Tissues." Current Molecular Pharmacology 4:135-140.

Morgan WF and MB Sowa. 2011. "What Have Omics Taught Us About the Health Risks Associated with Exposure to Low Doses of Ionizing Radiation." In Cancer Risk Evaluation: Methods and Trends, pp. 233-244, G Obe, GE Marchant, B Jandrig, H Schutz, and PM Wiedemann, Editors. Wiley-VCH Verlag GmbH & Co. KGaA. DOI:10.1002/9783527634613.ch15.

Shankaran H, WB Chrisler, RL Sontag, and TJ Weber. 2011. "Inhibition of ERK Oscillations by Low Dose Ionizing Radiation and Reactive Oxygen Species." Molecular Carcinogenesis 50(6):424-32.

Sowa MB, W Goetz, JE Baulch, AJ Lewis, and WF Morgan. 2011. "No Evidence for a Low Linear Energy Transfer Adaptive Response in Irradiated RKO Cells." Radiation Protection Dosimetry 143:311- 314.

Varnum SM, MB Sowa, GJ Kim, and WF Morgan. 2011. "Radiation-induced Genomic Instability and Radiation Sensitivity." In Encyclopedia of Radiation Oncology (in press).


Dauer LT, AL Brooks, DG Hoel, WF Morgan, D Stram, and P Tran. 2010. "Review and Evaluation of Updated Research on the Health Effects Associated with Low-Dose Ionizing Radiation." Radiation Protection Dosimetry 140:103-136.

Morgan WF and MB Sowa. 2009. "Non-Targeted Effects of Ionizing Radiation: Implications for Risk Assessment and the Radiation Dose Response Profile." Health Physics 97:426-432.

Ramos KS and TJ Weber. 2010. "Overview of Alterations in Cell Signaling." In Elsevier's Comprehensive Toxicology, 2nd ed., Charlene A. McQueen, Editor. The Boulevard, Langford Lane, Kidlington OX5 1GB, United Kingdom.

Sowa MB, WB Chrisler, KD Zens, EJ Ashjian, and LK Opresko. 2010. "Three-dimensional Culture Conditions Lead to Decreased Radiation Induced Crytoxicity in Human Mammary Epithelial Cells." Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis 687:78-83.

Sowa MB, W Goetz, JE Baulch, DN Pyles, J Dziegielewski, S Yovino, AR Snyder, SM de Toledo, EI Azzam, and WF Morgan. 2010. "Lack of Evidence for Low-LET Radiation Induced Bystander Response in Normal Human Fibroblasts and Colon Carcinoma Cells." International Journal of Radiation Biology 86:102-113.

Tian Z, R Zhao, N Tolic, RJ Moore, DL Stenoien, EW Robinson, RD Smith, and L Pasa-Tolic. 2010. "A Metal-Free Two-Dimensional Liquid Chromatography System for Online Top-Down Mass Spectrometry." Proteomics 10:3610-3620.

Weber TJ, H Shankaran, HS Wiley, LK Opresko, WB Chrisler, and RD Quesenberry. 2010. "Basic Fibroblast Growth Factor Regulates Persistent ERK Oscillations in Premaligant but not Malignant JB6 Cells." Journal of Investigative Dermatology 130:144-156.

Weber TJ. 2010. "Protein Kinases." In Elsevier's Comprehensive Toxicology, 2nd ed. Charlene A. McQueen, Editor. The Boulevard, Langford Lane, Kidlington OX5 1GB, United Kingdom.

Yang F, KM Waters, JH Miller, MA Gritsenko, R Zhao, X Du, EA Livesay, SO Purvine, ME Monroe, DG Camp, II, RD Smith, and DL Stenoien. 2010. "Phosphoproteomic Profiling of Human Skin Fibroblast Cells Reveals Pathways and Proteins Affected by Low Doses of Ionizing Radiation." PLOS One 5(11):e14152.


Brooks AL, PE Eberline, LA Couch, BB Boecker. 2009. "The Role of Dose-Rate on Risk from Internally- deposited Radionuclides and the Potential need to Separate Dose-rate Effectiveness Factor (DREF) from the Dose and Dose-rate Effectiveness Factor (DDREF)." Health Physics 97:458-469.

Waters KM, R Tan, LK Opresko, RD Quesenberry, S Bandyopadhyay, WB Chrisler, and TJ Weber. 2009. "Cellular Dichotomy between AIG Responses to bFGF and TPA Reflects Molecular Switch in Commitment to Carcinogenesis." Molecular Carcinogenesis 48:1059-1069.

Weber TJ, LK Opresko, DM Waisman, GJ Newton, RD Quesenberry, N Bollinger, RJ Moore, and RD Smith. 2009. "Regulation of the Low Dose Radiation Paracrine-Specific Anchorage-Independent Growth Response by Annexin A2." Radiation Research 172:96-105.

Yang F, S Wu, DL Stenoien, R Zhao, ME Monroe, MA Gritsenko, SO Purvine, AD Polpitiya, N Tolic, Q Zhang, AD Norbeck, DJ Orton, RJ Moore, K Tang, GA Anderson, L Pasa-Tolic, DG Camp, II, and RD Smith. 2009. "Combined Pulsed-Q Dissociation and Electron Transfer Dissociation for Identification and Quantitation of iTRAQ-labeled Phosphopeptides." Analytical Chemistry 81:4137-4143.

PNNL's Low Dose Radiation Research Program


Fundamental & Computational Sciences



DOE Program Manager
Noelle Metting

BER Sector Manager
Harvey Bolton

Principal Investigator
Bill Morgan

Science Advisor
Tony Brooks