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Staff information

Bingwen Liu

Instrument Development Lab
Post Doctorate RA C
Pacific Northwest National Laboratory
PO Box 999
MSIN: K8-91
Richland, WA 99352


Dr Bingwen Liu's research is focused on the development of novel microfluidic devices and their applications in chemical/biololgical analysis and sensing. He has long time of experience in microfabircation in cleanroom. He is also active in Comsol Multiphysics modeling and other modeling tools to validate experimental results. Past research includes crystallization and uncleation for pharmaceutical production improvement, as well as ion selective electrodes for environmentally relevant ion detection.

Research Interests

  • Microfluidics (Lab on a chip)
  • Microelectromechanical systems (MEMS)
  • Electrophoresis
  • Biosensors
  • Material engineering

Education and Credentials

  • Ph.D. Chemical Engineering, Washington State University
  • M.S. Chemical Engineering, Washington State Univeristy
  • M.S. Chemical Engineering, Tianjin Univeristy
  • B.S. Chemical Engineering, Nanjing University of Technology

Affiliations and Professional Service

  • American Institute of Chemical Engineers
  • American Electrophoresis Society
  • Sigma Xi

PNNL Publications


  • Wang Z, B Liu, E Zhao, K Jin, Y Du, JJ Neeway, JV Ryan, D Hu, H Zhang, M Hong, S Le Guernic, S Thevuthasan, F Wang, and Z Zhu. 2015. "Argon Cluster Sputtering Source for ToF-SIMS Depth Profiling of Insulating Materials: High Sputter Rate and Accurate Interfacial Information." Journal of the American Society for Mass Spectrometry 26(8):1283-1290.  doi:10.1007/s13361-015-1159-1


  • Hua X, XY Yu, Z Wang, L Yang, B Liu, Z Zhu, AE Tucker, WB Chrisler, EA Hill, S Thevuthasan, Y Lin, S Liu, and MJ Marshall. 2014. "In situ molecular imaging of hydrated biofilm in a microfluidic reactor by ToF-SIMS." Analyst 139:1609-1613.  doi:10.1039/C3AN02262E
  • Liu B, D Du, X Hua, XY Yu, and Y Lin. 2014. "Papers Based Electrochemical Biosensors: From Test Strips to Paper-Based Microfluidics." Electroanalysis 26(6):1214-1223.  doi:10.1002/elan.201400036
  • Liu B, XY Yu, Z Zhu, X Hua, L Yang, and Z Wang. 2014. "In situ chemical probing of the electrode-electrolyte interface by ToF-SIMS." Lab on a Chip 14(5):855-859.  doi:10.1039/C3LC50971K

Selected Publications


  • Bingwen Liu, Xiao-Ying Yu, Zihua Zhu, Xin Hua, Li Yang, and Zhaoying Wang, In situ chemical probing of the electrode-electrolyte interface by ToF-SIMS, Lab on a Chip, 14(5), 855-859, 2014, DOI:10.1039/C3LC50971K.
  • Yongzheng Cong, Danny Bottenus, Bingwen Liu, Sue B. Clark, Cornelius F. Ivory. Isotachophoresis of lanthanides in microfluidic PMMA chip. Electrophoresis, 35(5), 646-653, 2014. DOI: 10.1002/elps.201300382.


  • Bingwen Liu, Cornelius F Ivory, Isotachophoresis with counterflow in an open capillary: computer simulation and experimental validation, Journal of Separation Science. 36(12), 1986-95, 2013. DOI: 10.1002/jssc.201300066
  • Xiao-Ying Yu, Bingwen Liu, and Li Yang. Imaging liquids using microfluidic cells. Microfluidics and Nanofluidics. 15, 725-744, 2013. DOI: 10.1007/s10404-013-1199-4


  • Daniel C. Rieck, Bingwen Liu, Bong-Jae Park, David F. Moffett, David A. Kidwell, Gary J. Cheng, Bernard J. Van Wie. Functionalization of micro- and nano-apertures with chromate-selective solvent polymeric membrane, Analytica Chimica Acta, 659, 243-250, 2010


  • Bingwen Liu, Daniel Rieck, Bernard J. Van Wie, Gary J. Cheng, David F. Moffett and David A. Kidwell, Bilayer lipid membrane (BLM) based ion selective electrodes at the meso-, micro-, and nano-scales, Biosensors and Bioelectronics, 24(7), 1843-1849, 2009


  • Bingwen Liu, Dongyun Wang, and Xiangrong Huang, Study on primary nucleation of benzathini benzylpenicillinum, Chemical Industry and Engineering, 20 (3), 175-177, 2003

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