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Staff information

William Chrisler

Biochemistry & Structural Biology
Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-02
Richland, WA 99352

PNNL Publications

2014

  • Cole JK, JR Hutchison, RS Renslow, YM Kim, WB Chrisler, HE Engelmann, A Dohnalkova, D Hu, TO Metz, JK Fredrickson, and SR Lindemann. 2014. "Phototrophic Biofilm Assembly in Microbial-Mat-Derived Unicyanobacterial Consortia: Model Systems for the Study of Autotroph-Heterotroph Interactions." Frontiers in Microbiology 5:Article No. 109.  doi:10.3389/fmicb.2014.00109
  • Hua X, XY Yu, Z Wang, L Yang, B Liu, Z Zhu, AE Tucker, WB Chrisler, EA Hill, S Thevuthasan, Y Lin, S Liu, and MJ Marshall. 2014. "In situ molecular imaging of hydrated biofilm in a microfluidic reactor by ToF-SIMS." Analyst 139:1609-1613.  doi:10.1039/C3AN02262E
  • Sadler NC, MR Melnicki, MH Serres, ED Merkley, WB Chrisler, EA Hill, MF Romine, S Kim, EM Zink, S Datta, RD Smith, AS Beliaev, A Konopka, and AT Wright. 2014. "Live Cell Chemical Profiling of Temporal Redox Dynamics in a Photoautotrophic Cyanobacterium." ACS Chemical Biology 9(1):291-300.  doi:10.1021/cb400769v
  • Wiedner SD, LN Anderson, NC Sadler, WB Chrisler, VK Kodali, RD Smith, and AT Wright. 2014. "Organelle-Specific Activity-Based Protein Profiling in Living Cells." Angewandte Chemie International Edition 53(11):2919-2922.  doi:10.1002/anie.201309135

2013

  • von Neubeck C, H Shankaran, M Geniza, PM Kauer, RJ Robinson, WB Chrisler, and MB Sowa. 2013. "Integrated Experimental and Computational Approach to Understand the Effects of Heavy Ion Radiation on Skin Homeostasis." Integrative Biology 5(10):1229-1243.  doi:10.1039/C3IB40071A
  • Welkie DG, DM Sherman, WB Chrisler, G Orr, and LA Sherman. 2013. "Analysis of carbohydrate storage granules in the diazotrophic cyanobacterium Cyanothece sp. PCC 7822." Photosynthesis Research 118(1-2):25-36.  doi:10.1007/s11120-013-9941-z

2012

  • Freiin von Neubeck CH, H Shankaran, NJ Karin, PM Kauer, WB Chrisler, X Wang, RJ Robinson, KM Waters, SC Tilton, and MB Sowa. 2012. "Cell Type-dependent Gene Transcription Profile in Three Dimensional Human Skin Tissue Model Exposed to Low Doses of Ionizing Radiation: Implications for Medical Exposures." Environmental and Molecular Mutagenesis 53(4):247-259.  doi:10.1002/em.21682
  • Jin H, Y Yu, WB Chrisler, Y Xiong, D Hu, and C Lei. 2012. "Delivery of MicroR A-10b with Polylysine Nanoparticles for Inhibition of Breast Cancer Cell Wound Healing." Breast Cancer: Basic and Clinical Research 6:9-19.  doi:10.4137/BCBCR.S8513
  • Shankaran H, Y Zhang, WB Chrisler, JA Ewald, HS Wiley, and H Resat. 2012. "Integrated Experimental and Model-based Analysis Reveals the Spatial Aspects of EGFR Activation Dynamics." Molecular Biosystems 8(11):2868-2882.  doi:10.1039/C2MB25190F
  • Waters KM, DL Stenoien, MB Sowa, CH Freiin Von Neubeck, WB Chrisler, R Tan, RL Sontag, and TJ Weber. 2012. "Annexin A2 Modulates Radiation-Sensitive Transcriptional Programming and Cell Fate." Radiation Research 179(1):56-61.  doi:10.1667/RR3056.1
  • Xie Y, NG Williams, A Tolic, WB Chrisler, JG Teeguarden, BL Maddux, JG Pounds, A Laskin, and G Orr. 2012. "Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface." Toxicological Sciences 125(2):450-461.  doi:10.1093/toxsci/kfr251

2011

  • Miller JH, WB Chrisler, X Wang, and MB Sowa. 2011. "Confocal Microscopy for Modeling Electron Microbeam Irradiation of Skin." Radiation and Environmental Biophysics 50(3):365-369.  doi:10.1007/s00411-011-0371-z
  • Miller JH, A Suleiman, WB Chrisler, and MB Sowa. 2011. "Simulation of Electron-Beam Irradiation of Skin Tissue Model." Radiation Research 175(1):113-118.  doi:10.1667/RR2339.1
  • Orr G, WB Chrisler, KJ Cassens, R Tan, BJ Tarasevich, LM Markillie, RC Zangar, and BD Thrall. 2011. "Cellular Recognition and Trafficking of Amorphous Silica Nanoparticles by Macrophage Scavenger Receptor A." Nanotoxicology 5(3):296-311.  doi:10.3109/17435390.2010.513836

2010

  • Weber TJ, H Shankaran, HS Wiley, LK Opresko, WB Chrisler, and RD Quesenberry. 2010. "Basic Fibroblast Growth Factor Regulates Persistent ERK Osciliations in Premaligant but not Malignant JB6 Cells." Journal of Investigative Dermatology 130(5):144-156. 
  • Hinderliter PM, KR Minard, G Orr, WB Chrisler, BD Thrall, JG Pounds, and JG Teeguarden. 2010. "ISDD: A Computational Model of Particle Sedimentation, Diffusion and Target Cell Dosimetry for In Vitro Toxicity Studies." Particle and Fibre Toxicology 7(November):Article No. 36.  doi:10.1186/1743-8977-7-36
  • Shankaran H, WB Chrisler, RL Sontag, and TJ Weber. 2010. "Inhibition of ERK Oscillations by Ionizing Radiation and Reactive Oxygen Species." Molecular Carcinogenesis 50(6):424-432.  doi:10.1002/mc.20724
  • Sowa MB, WB Chrisler, KD Zens, EJ Ashjian, and LK Opresko. 2010. "Three-dimensional Culture Conditions Lead to Decreased Radiation Induced Crytoxicity in Human Mammary Epithelial Cells." Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis 687(1-2):78-83.  doi:10.1016/j.mrfmmm.2010.03.004

2009

  • Karagiosis SA, WB Chrisler, N Bollinger, and NJ Karin. 2009. "Lysophosphatidic Acid-induced ERK Activation and Chemotaxis in MC3T3-E1 Preosteoblasts are Independent of EGF Receptor Transactivation." Journal of Cellular Physiology 219(3):716-723. 
  • Shankaran H, DL Ippolito, WB Chrisler, H Resat, N Bollinger, LK Opresko, and HS Wiley. 2009. "Rapid and Sustained Nuclear-Cytoplasmic ERK Oscillations Induced by Epidermal Growth Factor." Molecular Systems Biology 5:Article Number: 332.  doi:10.1038/msb.2009.90
  • Waters KM, R Tan, LK Opresko, RD Quesenberry, S Bandyopadhyay, WB Chrisler, and TJ Weber. 2009. "Cellular Dichotomy Between Anchorage-Independent Growth Responses to bFGF and TA Reflects Molecular Switch in Commitment to Carcinogenesis." Molecular Carcinogenesis 48(11):1059-1069. 
  • Zhang Y, LK Opresko, H Shankaran, WB Chrisler, HS Wiley, and H Resat. 2009. "HER/ErbB Receptor Interactions and Signaling Patterns in Human Mammary Epithelial Cells." BMC Cell Biology 10 :Article No. 78.  doi:10.1186/1471-2121-10-78

2007

  • Coleman JR, DE Culley, WB Chrisler, and FJ Brockman. 2007. "mRNA-targeted Fluorescent in Situ Hybridization (FISH) of Gram-negative Bacteria Without Template Amplification or Tyramide Signal Amplification." Journal of Microbiological Methods 71(3):246-255.  doi:10.1016/j.mimet.2007.09.011

2005

  • Weber TJ, RW Siegel, LM Markillie, WB Chrisler, XC Lei, and NH Colburn. 2005. "A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells ." Molecular Carcinogenesis 43(1):31-37. 
  • Dong J, L Opresko, WB Chrisler, G Orr, RD Quesenberry, DA Lauffenburger, and HS Wiley. 2005. "The Membrane-anchoring Domain of Epidermal Growth Factor Receptor Ligands Dictates Their Ability to Operate in Juxtacrine Mode." Molecular Biology of the Cell 16(6):2984-2998. 

2004

  • Jasionowski M, KJ Krzyminski, WB Chrisler, LM Markillie, JE Morris, and A Gutowska. 2004. "Thermally-reversible gels for 3D cell culture of chondrocytes." Journal of Materials Science. Materials in Medicine 15(5):575-582. 

2002

  • Weber TJ, LM Markillie, WB Chrisler, GA Vielhauer, and JW Regan. 2002. "Modulation of JB6 Mouse Epidermal Cell Transformation Response by the Prostaglandin F2 alpha Receptor." Molecular Carcinogenesis 35(4):163-172. 
  • Weber TJ, LM Markillie, WB Chrisler, GA Vielhauer, and JW Regan. 2002. "Modulation of JB6 Mouse Epidermal Cell Transformation Response by the Prostaglandin F2 Alpha Receptor." Molecular Carcinogenesis 35(4):163-172. 

2001

  • Conrads TP, K Alving, TD Veenstra, ME Belov, GA Anderson, DJ Anderson, MS Lipton, L Pasa-Tolic, HR Udseth, WB Chrisler, BD Thrall, and RD Smith. 2001. "Quantitative Analysis of Bacterial and Mammalian Proteomes using a Combination of Cysteine Affinity Tags and 15N-Metabolic Labeling." Analytical Chemistry 73(9):2132-2139. 
  • Gutowska A, M Jasionowski, JE Morris, WB Chrisler, YH An, and V Mironov. 2001. "Polymer Formulations for Cartilage Repair." In Transactions: 27th annual meeting, Society for Biomaterials, in conjunction with the 33rd International Biomaterials Symposium, vol. 24, ed. LT Khun and CM Agrawal, p. 566.  Society for Biomaterials, Minneapolis, MN. 

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