PNNL's Low Dose Radiation Research Program Scientific Focus Area
Experimental designs are developed to interrogate complex signaling in human skin tissue.Linear and Nonlinear Tissue-Signaling Mechanisms in Response to Low Dose and Low Dose-Rate Radiation
This program is funded as a U.S. Department of Energy Scientific Focus Area (SFA), and is an integrated cooperative program to understand low dose radiation effects in a complex model system.
Goal
The goal of PNNL's Low Dose Radiation (LDR) Program is to develop a systems-level predictive understanding of LDR, low dose-rate (LDRt) effects by defining the molecular response of tissues to LDR and extending these experimental findings to studies addressing their consequences on tissue homeostasis and pathophysiology.
Objectives
These objectives are supported by Data Integration & Computational Modeling.
The program has three objectives