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Biological Sciences
  • James Stegen

    Article Named Top 100 of 2015 by Frontiers Blog

    Congratulations to James Stegen and Jim Fredrickson whose research article "Estimating and Mapping Ecological Processes Influencing Microbial Community Assembly" was named among the top "100 Articles from 2015 in the Spotlight" by Frontiers Blog one of the largest and fastest-growing community-rooted, open-access academic publishers.

  • vitamin mimic binding to protein

    Microbes Take Their Vitamins—for the Good of Science

    Scientists at Pacific Northwest National Laboratory have made a "vitamin mimic"—a molecule that looks and acts just like the natural vitamin to bacteria, but can be tracked and measured in live cells. The research offers a new window into the inner workings of living microbes crucial to the world's energy future, wielding great influence in the planet's carbon and nutrient cycle and serving as actors in the creation of new fuels.

  • Mouse macrophage images

    Scientists Pinpoint One Way Nanoparticles Damage Immune Cells

    PNNL scientists have shown that a process known as oxidative stress is at work during encounters between certain nanoparticles and immune cells, selectively modifying proteins on macrophages, a type of immune cell. The findings were published in ACS Nano.

  • image in yeast

    Optimizing Biofuel Production in Yeast

    PNNL researchers performed the first comprehensive metabolomics and lipidomics study on the yeast species Yarrowia lipolytica to characterize metabolic processes associated with lipid accumulation, which gives the yeast strong potential as a biofuel-producing organism. They identified and characterized major pathways involved in lipid accumulation from glucose in Y. lipolytica.

  • Image of genomes in microbial community

    The Truth about Microdiversity

    Tiny microbes are hiding big secrets. Scientists often use a collection or community of microbes to study molecular functions, but the more complex the community, the more difficult it is to tease out functions and interactions. Now, scientists at Pacific Northwest National Laboratory have peered into two microbial communities of blue-green algae to collect near-complete genomic information for all 20 members in each community.

About The Division

Scientists within the Biological Sciences Division perform biological systems science research and develop technologies focused on how cells, cell communities, and organisms sense and respond to their environment. Our vision is to measure, predict, design, and control multi-cellular biological systems and bio-inspired solutions for energy, environment, and health.

Our investigator-initiated and multi-institutional collaborative research, unique scientific instrumentation, and national program leadership translate the latest scientific discoveries into technologies that are beneficial to the nation.

Our research has applications to energy, environment, and human health missions of the U.S. Department of Energy (DOE), the National Institutes of Health (NIH), and other federal agencies.

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Biological Sciences

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